Assessment of perioperative nutrition practices and attitudes-A national survey of colorectal and GI surgical oncology programs.
J D Williams, Paul E Wischmeyer
https://pubmed.ncbi.nlm.nih.gov/27889271/Actively Recruiting
Led by Dartmouth-Hitchcock Medical Center · Updated on 2026-02-11
100
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are studying older adults aged 70 years and above who are undergoing major orthopedic or abdominal surgery. The study evaluates whether giving a specially designed nutritional shake after surgery can help improve physical function and cognitive abilities during recovery. This trial aims to gather data on the role of nutrition in recovery for frail older surgical patients, with the goal of informing future larger studies on optimizing recovery through nutritional support. Participants will be randomly assigned to one of two groups. One group will receive standard nutritional instructions after surgery, while the other group will receive the same instructions plus a daily nutritional shake for 30 days following hospital discharge. The shake contains a balanced mix of essential nutrients, including protein, cocoa flavanols, omega-3 fatty acids, choline, polyphenols, and multivitamins to support muscle, metabolic, and brain health. During the study, participants demographics, medical history, and medication use will be collected. Researchers will assess physical function and cognitive abilities while participants are in the hospital and again 90 days after surgery. Participants in the shake group will track their daily shake intake through logs submitted online, which the study team will review for adherence and any side effects. The main outcomes measured are changes in disability and cognitive function 90 days after surgery, with ongoing monitoring throughout the study period.
CONDITIONS
Nutrition to Support Postoperative Recovery
S
Stacie G Deiner, MD
A
Alexander R Roth, BA
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Dartmouth-Hitchcock Medical Center
Lead Sponsor
Hitchcock Foundation
Collaborating Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Nutritional Shake and Postoperative Instructions | Postoperative Nutrition Instructions Only |
|---|---|---|
| What it is | A nutrition intervention providing a daily shake with cocoa flavanols, protein, omega-3 fatty acids, choline, plant polyphenols, and a broad range of micronutrients, together with written instructions on healthy eating after surgery. | Written guidelines for healthy nutrition after surgery, without any additional nutritional supplementation. |
| Role in the trial | Evaluated to see whether adding a targeted nutritional shake to instruction can improve physical function and cognition after major surgery in older adults. | Serves as the comparison (control) group for evaluating the effects of additional nutritional supplementation. |
| Primary use | Intended to support recovery and reduce complications following major orthopedic or abdominal surgery in people aged 70 years or older. | Aims to provide standard nutrition advice for postoperative recovery, reflecting usual education provided after surgery. |
| How it is given or performed | Participants receive pre-portioned daily shake mixes and nutrition instructions for use at home for 30 days after discharge. | Participants receive written postoperative nutrition instructions but do not receive any shake or supplement. |
| Evidence status | Evidence on the effectiveness of the specific shake for recovery after major surgery in older adults is emerging; final trial results are not yet available. | Written nutrition instructions are the current recommended approach for general postoperative recovery in older surgical patients. |
| Important limitations | The trial shake formula is investigational, and its benefit and tolerability in older adults after surgery remain to be determined. Not all patients may tolerate caffeine or the shake’s ingredients. | Written nutrition instructions depend on the patient's ability to understand and implement dietary advice, and may not be sufficient for all patients at risk of postoperative nutritional problems. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Hospital stay (at least one overnight)
Participants undergo elective major abdominal or orthopedic surgery and receive immediate post-operative care during their hospital stay.
1 hospitalization period
Duration - 30 days after hospital discharge
Participants in the intervention arm receive a daily nutritional shake starting upon hospital discharge, along with nutritional instructions. The control arm receives nutritional instructions only. Participants are instructed to consume the shake daily for 30 days and track their consumption.
1 visit at discharge and daily self-administration at home
Duration - Up to 90 days after surgery
Participants are monitored for postoperative recovery, including disability and cognitive function, up to 90 days after surgery.
Follow-up visits as scheduled for assessments
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
Have more questions? Get in touch with our team for quick support
J D Williams, Paul E Wischmeyer
https://pubmed.ncbi.nlm.nih.gov/27889271/Olle Ljungqvist, Michael Scott, Kenneth C Fearon
https://pubmed.ncbi.nlm.nih.gov/28097305/Robert D Becher, Brent Vander Wyk, Linda Leo-Summers...
https://pubmed.ncbi.nlm.nih.gov/34261884/Terri R Fried, Mary E Tinetti, Lynne Iannone...
https://pubmed.ncbi.nlm.nih.gov/21949032/D Janet Pavlin, Michael J L Sullivan, Peter R Freund...
https://pubmed.ncbi.nlm.nih.gov/15599135/Lisbeth Evered, Brendan Silbert, David A Scott...
https://pubmed.ncbi.nlm.nih.gov/29459944/Stacie Deiner, Mark G Baxter, Joshua S Mincer...
https://pubmed.ncbi.nlm.nih.gov/32536445/Susan B Roberts, Maria A Franceschini, Rachel E Silver...
https://pubmed.ncbi.nlm.nih.gov/32699176/Mindy J Katz, Cuiling Wang, Caroline O Nester...
https://pubmed.ncbi.nlm.nih.gov/33598528/M P Lawton, E M Brody
https://pubmed.ncbi.nlm.nih.gov/5349366/Dartmouth-Hitchcock Medical Center
Lead Sponsor
Hitchcock Foundation
Collaborating Sponsor