Actively Recruiting
Nutritional Intervention for Biliary Atresia
Led by Tongji Hospital · Updated on 2025-12-22
120
Participants Needed
1
Research Sites
204 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Infants with biliary atresia (Biliary atresia, BA) have an increased risk of malnutrition due to insufficient dietary intake to maintain normal growth, impaired intestinal absorption, increased metabolic rate, and damage to some liver macronutrient metabolic pathways. The medium-chain triglyceride formula (MCT) in enteral nutrition has advantages: (1) It has a fast metabolism in the liver and possesses the advantage of being an innate energy source; (2) It can share metabolic pathways with some other fatty acids (DHA, EPA), and can promote the synthesis of phospholipids, etc. Therefore, EN containing the MCT formula is regarded as an important approach to alleviate growth retardation in BA children and improve the nutritional status of patients. This study aims to observe the effect of intensified enteral feeding with a high MCT formula during the perioperative period compared to traditional oral feeding on the prognosis of children with biliary atresia. The method adopted is a prospective, two-arm, open-label, multicenter, and interventional real-world study.
CONDITIONS
Official Title
Nutritional Intervention for Biliary Atresia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Infants under 3 months old
- Clinically diagnosed with biliary atresia and scheduled for Kasai surgery
- Signed informed consent by patient, legal representative, or guardian and willing to cooperate with treatment and follow-up
You will not qualify if you...
- Low birth weight or very low birth weight infants
- Life-threatening diseases affecting various organ systems
- Severe digestive tract malformations or other diseases interfering with treatment or compliance
- Participation in other clinical trials within the last month
- Any condition deemed unsuitable by the researcher
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Tongji Hospital
Wuhan, Hubei, China, 430030
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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