Actively Recruiting
Nutritional Intervention for Endometriosis
Led by Physicians Committee for Responsible Medicine · Updated on 2026-04-23
120
Participants Needed
1
Research Sites
404 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In a 12-week parallel study, women with a verified diagnosis of endometriosis will be randomly assigned to follow a low-fat plant-based diet or to stay on their usual diets for 12 weeks. Participants in both groups will be asked to make no changes to their exercise patterns for the study period. Changes in pain, quality of life, and inflammatory biomarkers from baseline to final will be the primary outcomes. Secondary outcomes will include changes in body weight, blood lipids, gut microbiome composition, and hormonal changes.
CONDITIONS
Official Title
Nutritional Intervention for Endometriosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women with a surgical, imaging, or clinical diagnosis of endometriosis
- Age 18-45 years
- Stable health condition and medications for past 3 months
- Modified Biberoglu and Behrman pelvic pain score of at least 5 out of 9
- Able to follow a plant-based diet for 12 weeks
- Willing to be randomly assigned to either a plant-based diet group or a control group with no dietary changes for 12 weeks
You will not qualify if you...
- Body mass index of 40 kg/m2 or higher
- Smoking or drug abuse within the past six months
- Alcohol use of more than 2 drinks per day or episodic heavy drinking, history of alcohol abuse or current use
- Unstable medical or psychiatric illness
- Already following a plant-based diet
- Pregnant, breastfeeding, or planning pregnancy during the study period
- History of hysterectomy or ovariectomy
- Presence of fibroids, ovarian cysts, or pelvic inflammatory disease
- Endocrine inflammatory diseases such as Cushing's syndrome, Hashimoto's thyroiditis, Graves' disease, type 1 diabetes mellitus, or Addison's disease
- Lack of fluency in English
- Unable or unwilling to participate in all study components
- Evidence of an eating disorder
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Physicians Committee for Responsible Medicine
Washington D.C., District of Columbia, United States, 20016
Actively Recruiting
Research Team
M
Macy Sutton, MS
CONTACT
T
Tatiana Znayenko-Miller, DrPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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