Actively Recruiting
Nutritional Prehabilitation to Improve Cancer Outcomes (N-PICO)
Led by University of Vermont Medical Center · Updated on 2026-02-05
240
Participants Needed
1
Research Sites
155 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Brief Summary The goal of this clinical trial is to evaluate the acceptability and adherence of low- and high-intensity remote nutritional interventions for cancer patients in rural and urban areas, specifically focusing on those with invasive cancer who are about to start treatment. The main question\[s\] it aims to answer are: Can low- and high-intensity remote nutritional interventions improve adherence to cancer treatment and quality of life? What is the impact of nutritional support on treatment delays, unplanned healthcare utilization, and dietary modifications? Researchers will compare the low-intensity arm (initial nutritional consultation plus written materials) to the high-intensity arm (1-hour consultation, monthly follow-ups, and written materials) to see if higher intensity interventions lead to better outcomes in terms of adherence, quality of life, and healthcare utilization. Participants will: Receive either a low- or high-intensity nutritional consultation. Complete surveys assessing quality of life, dietary habits, treatment delays, and unplanned healthcare use. Be asked to participate in monthly follow-up consultations (for the high-intensity group) to track progress and provide additional support.
CONDITIONS
Official Title
Nutritional Prehabilitation to Improve Cancer Outcomes (N-PICO)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of invasive cancer with plans to start chemo-, immune-, targeted-, or hormonal therapy, or within one month of starting treatment
- Age 18 years or older
- Ability to read, write, and speak English
- Receiving treatment at a participating ambulatory medical oncology site
- Willingness to have a remote nutritional consultation and complete surveys
- Signed informed consent according to institutional and federal guidelines
You will not qualify if you...
- Diagnosis of acute leukemia
- Diagnosis of head and neck cancer, esophageal cancer, or gastric cancer
- Presence of recognized cachexia or severe malnutrition
- Having a PEG tube for enteral feeding
- Need for ongoing clinical intervention from an on-site dietitian beyond the study period
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Vermont Medical Center
Burlington, Vermont, United States, 05401
Actively Recruiting
Research Team
R
Randall F Holcombe, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
6
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