Actively Recruiting
Nutritional Supplementation in Head and Neck Cancers
Led by AHS Cancer Control Alberta · Updated on 2025-03-28
81
Participants Needed
1
Research Sites
100 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to determine whether multimodal nutrition therapy (primary nutrition intervention + adjuvant nutrition therapy) will support patients to optimize their total caloric intake during cancer treatment by measuring the difference in mean cumulative energy intake between the intervention and control group over the duration of cancer treatment.
CONDITIONS
Official Title
Nutritional Supplementation in Head and Neck Cancers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability to read, understand, and sign informed consent and willingness to comply with study treatment and follow-up
- Male or female
- At least 18 years of age
- Histopathologically confirmed primary squamous cell carcinoma of the oral cavity, oropharynx, larynx, or hypopharynx
- Planned radical intent radiotherapy as primary or adjuvant treatment, with or without platinum chemotherapy
- Able to eat by mouth at baseline
- Diagnostic CT scan within 30 days before starting radiotherapy, or baseline non-contrast CT abdomen if no recent scan
- Eastern Cooperative Oncology Group Performance Status of 2 or less
You will not qualify if you...
- Fed by nasogastric tube, gastrostomy, or total parenteral nutrition
- Cancer of the nasopharynx, thyroid, or salivary gland
- Life expectancy less than 6 months
- Known allergy or hypersensitivity to the investigational product or its ingredients (e.g., milk/lactose, fish)
- Enrolled in other clinical trials with interventional agents or assessments that could interfere
- Untreated brain metastases (previously treated brain metastases without symptoms allowed)
- Poorly controlled chronic illnesses or inflammatory diseases (e.g., COPD, uncontrolled diabetes, rheumatoid arthritis)
- Medical conditions affecting nutrient metabolism or absorption (e.g., short bowel syndrome, Crohn's disease)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cross Cancer Institute
Edmonton, Alberta, Canada, T6G 1Z2
Actively Recruiting
Research Team
V
Vickie Baracos
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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