Actively Recruiting
Obesity, Insulin Resistance, and PASC: Persistent SARS-CoV-2
Led by Stanford University · Updated on 2024-12-04
55
Participants Needed
2
Research Sites
134 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The investigators are studying the pathophysiologic links between obesity, insulin resistance (IR), adipose tissue infection, and post-acute sequelae of COVID-19 (PASC). This study looks at whether adipose (fat) tissue contributes to PASC by driving chronic inflammation or by serving as a reservoir for SARS-CoV-2 persistence. The results will not only determine whether obesity and IR are risk factors for PASC, but will also define fundamental biology that sets the stage for the investigation of novel or existing therapies that target the causal pathways identified.
CONDITIONS
Official Title
Obesity, Insulin Resistance, and PASC: Persistent SARS-CoV-2
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 18 to 80
- Body mass index (BMI) of 25 kg/m2 or higher
- Not currently pregnant
You will not qualify if you...
- Pregnancy
- Prior liposuction
- Recent weight change greater than 2 kg in one month
- Bleeding disorders
- Use of anticoagulant medications
- Major organ disease (for healthy controls)
- Diabetes (for healthy controls)
- History of liposuction (for healthy controls)
- Bariatric surgery (for healthy controls)
- Eating disorders (for healthy controls)
- Psychiatric disorders (for healthy controls)
- Pregnancy or breastfeeding (for healthy controls)
- Recent weight change over the past 12 weeks (for healthy controls)
- Use of weight loss medication or oral steroids (for healthy controls)
- Low hematocrit below 33% (for healthy controls)
- Fasting blood glucose of 126 mg/dL or higher (for healthy controls)
- High blood pressure above 160/100 mmHg (for healthy controls)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Clinical and Translational Research Unit
Palo Alto, California, United States, 94304
Enrolling by Invitation
2
Stanford Health
Palo Alto, California, United States, 94305
Actively Recruiting
Research Team
N
Nicole Turk, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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