Actively Recruiting
Objective Concussion Assessment Using MRI and Metabolomics
Led by St. Joseph's Healthcare Hamilton · Updated on 2025-05-15
100
Participants Needed
1
Research Sites
174 weeks
Total Duration
On this page
Sponsors
S
St. Joseph's Healthcare Hamilton
Lead Sponsor
M
McMaster University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Mild traumatic brain injury (mTBI), also referred to as concussions, affect millions of people around the world and can cause harmful long term effects. Unfortunately, concussions can be hard to diagnose and many people have lasting post-concussion symptoms such as headaches, difficulty concentrating, and light sensitivity. Recent studies have shown that advanced magnetic resonance imaging (MRI) techniques can identify subtle brain changes caused by a concussion. This study aims to track concussions over time measuring MRI brain scans and post-concussion symptoms to gain a better understand how the brain is affected in comparison to symptoms.
CONDITIONS
Official Title
Objective Concussion Assessment Using MRI and Metabolomics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 9-50
- Recently sustained a concussion (within the last 2 weeks)
You will not qualify if you...
- Aged 8 and younger or 51 and older
- Unable to provide consent (e.g., poor English language skills, etc.)
- History of liver or kidney disease
- MRI contraindications including pacemaker, stent, joint prosthesis, implanted devices, claustrophobia, pregnancy, or permanent piercings
- Chronic or abusive use of alcohol and/or illicit drugs
- Previous stroke or moderate/severe traumatic brain injury, subarachnoid hemorrhage, or intracranial hemorrhage
- Healthy control participants must not have a concussion history or recently sustained a concussion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Imaging Research Center at St. Joseph's Healthcare Hamilton
Hamilton, Ontario, Canada, L8N 4A6
Actively Recruiting
Research Team
M
Michael D Noseworthy, PhD, PEng
CONTACT
E
Ethan Danielli, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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