Study of How Environment Affects Hormones and Reproductive Health in People Aged 8 and Older

What this Trial Is About

Researchers are investigating how environmental factors like pollution, chemical exposure, foods, medicines, and sleep habits may affect the endocrine and reproductive systems. The study focuses on individuals with hormone-related conditions such as hypogonadism, infertility, and other reproductive disorders. It aims to explore the possible links between internal and external environmental exposures and reproductive and endocrine dysfunction over time. Participants include males and females aged 8 years and older with various reproductive endocrine disorders, including polycystic ovary syndrome, hypogonadism, delayed or precocious puberty, and other related conditions. Children may participate until age 23, with up to 12 visits over five years, while adults may have 4 to 5 visits during the same period. During visits, participants undergo physical exams, blood and urine tests, questionnaires about diet and health, and sometimes additional tests like imaging scans or semen analysis. Throughout the study, researchers will collect data on body composition, resting energy expenditure, nutrition, stress, and psychological factors related to reproductive health. Most visits last less than three hours. The main goal is to assess how environment and lifestyle relate to reproductive neuroendocrinology at baseline and after clinical care. The study includes ongoing monitoring and data collection to better understand reproductive and endocrine health over time.

Observation of Environment and Reproductive-Endocrine Effects