Actively Recruiting
Observation Study to Evaluate the Efficacy and Safety of Ifosfamide/Mesna in Patients With Metastatic Castration-resistant Prostate Cancer
Led by Yonsei University · Updated on 2024-02-01
60
Participants Needed
1
Research Sites
521 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Prostate cancer is the 2nd most common cancer in men worldwide. Based on the results of several recent clinical trials, systemic treatments including hormone inhibitors, docetaxel, cabazitaxel, and PARP inhibitors are being used as standard treatment for patients with metastatic castration-resistant prostate cancer. However, there is insufficient research on salvage therapy for patients with metastatic castration-resistant prostate cancer who have failed standard treatment. In this study, the investigators will evaluate the effectiveness and safety of ifosfamide in castration-resistant prostate cancer by analyzing the treatment outcomes of patients who received ifosfamide/mesna treatment as salvage therapy.
CONDITIONS
Official Title
Observation Study to Evaluate the Efficacy and Safety of Ifosfamide/Mesna in Patients With Metastatic Castration-resistant Prostate Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male adults aged 19 years and older
- Histologically confirmed prostate cancer
- Castration-resistant prostate cancer
- ECOG performance status of 2 or less
- Previous exposure to docetaxel treatment
- Available prostate specific antigen (PSA) level
- Evaluable disease based on RECIST 1.1 criteria
You will not qualify if you...
- Diagnosis of other primary cancers within the past 3 years, except prostate cancer
- History of organ transplantation
- Hormone-sensitive prostate cancer
- ECOG performance status of 3 or higher
- No previous docetaxel exposure
- Previous exposure to ifosfamide
- No available PSA level
- Disease not evaluable by RECIST 1.1 criteria
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea
Seoul, South Korea
Actively Recruiting
Research Team
S
Sang Joon Shin
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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