Actively Recruiting

Age: 18Years +
All Genders
NCT03764124

Observation Study for Prediction of Allograft Survival and Impact of Imaging in Kidney Transplant Recipients.

Led by University of Liege · Updated on 2024-05-09

1000

Participants Needed

1

Research Sites

917 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To further develop personalized medicine in kidney transplantation and improve transplant patient outcomes, attention has been given to define early surrogate endpoints that might aid therapeutic interventions, and help clinical decision-making. To adequately predict transplant patients' individual risks of allograft loss and patients' complications, this would require a complex integration of data, including: donor data, recipient characteristics, transplant characteristics, biopsies results, immunosuppressive regimen, allograft infections, acute kidney injuries, recipient immune profiles, protocol and per cause biopsies and imaging (PET/CT imaging). This project aims: 1. Assessed the usefulness of 18F-FDG PET/CT imaging in kidney transplantation recipients presenting with suspected acute rejection who underwent a transplant needle biopsy; 2. To develop a prognostic risk score to predict kidney allograft survival; 3. To evaluate the impact of corticoids withdrawal on long term outcomes (risk of rejection and impact on bone mineral density); 4. Evaluate the type and the frequencies of complications in our kidney transplant population

CONDITIONS

Official Title

Observation Study for Prediction of Allograft Survival and Impact of Imaging in Kidney Transplant Recipients.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Kidney recipient transplanted after 2007
  • Kidney recipient over 18 years of age
  • Clinical, biological, immunological and follow up data available
Not Eligible

You will not qualify if you...

  • Combined transplantation

AI-Screening

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Trial Site Locations

Total: 1 location

1

Centre Hospitalier Universitaire de Liège

Liège, Belgium, 4000

Actively Recruiting

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Research Team

A

Antoine Bouquegneau, MD

CONTACT

L

Laurent Weekers, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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