Actively Recruiting
An Observational Study to Assess Change in Disease Activity and Adverse Events in Adolescent and Adult Participants With Moderate to Severe Active Crohn's Disease (CD) in Japan
Led by AbbVie · Updated on 2026-02-24
240
Participants Needed
104
Research Sites
196 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Crohn's disease (CD) is an incurable chronic inflammatory disorder of the gastrointestinal tract. This study will assess how safe and effective upadacitinib is in treating moderately to severely active CD in real world. Adverse events and change in disease activity will be assessed. Upadacitinib is a drug approved for the treatment of CD. All study participants will receive upadacitinib as prescribed by their study doctor in accordance with approved local label. Approximately 240 participants will be enrolled in Japan. Participants will receive upadacitinib as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed for up to 64 weeks. There is expected to be no additional burden for participants in this trial. Study visits may be conducted on-site or virtually as per standard of care.
CONDITIONS
Official Title
An Observational Study to Assess Change in Disease Activity and Adverse Events in Adolescent and Adult Participants With Moderate to Severe Active Crohn's Disease (CD) in Japan
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with moderately to severely active Crohn's disease (CD).
- Prescribed upadacitinib for CD according to the most current local approved label in Japan.
- Started upadacitinib induction treatment for CD within 14 days at the participating institution.
You will not qualify if you...
- Currently participating in another interventional clinical research.
- Upadacitinib is contraindicated for the participant.
- Previously treated with upadacitinib for CD before this study and continuing treatment at enrollment.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 104 locations
1
Anjou Kousei Hospital /ID# 261872
Anjo-shi, Aichi-ken, Japan, 446-8602
Actively Recruiting
2
Handa City Hospital /ID# 270446
Handa, Aichi-ken, Japan, 475-8599
Actively Recruiting
3
Aichi Medical University Hospital /ID# 261871
Nagakute, Aichi-ken, Japan, 480-1195
Actively Recruiting
4
Masuko Memorial Hospital /ID# 267420
Nagoya, Aichi-ken, Japan, 453-0016
Actively Recruiting
5
Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital /ID# 276219
Nagoya, Aichi-ken, Japan, 453-8511
Actively Recruiting
6
Nagoya City University Hospital /ID# 275588
Nagoya, Aichi-ken, Japan, 467-8602
Actively Recruiting
7
Toyohashi Municipal Hospital /ID# 274975
Toyohashi, Aichi-ken, Japan, 441-8570
Actively Recruiting
8
Ieda Hospital /ID# 259754
Toyota-shi, Aichi-ken, Japan, 470-1219
Actively Recruiting
9
Hachinohe City Hospital /ID# 264183
Hachinohe, Aomori, Japan, 031-0011
Actively Recruiting
10
Tsujinaka Hospital - Kashiwanoha /ID# 262648
Kashiwa-shi, Chiba, Japan, 277-0871
Actively Recruiting
11
Matsuyama Red Cross Hospital /ID# 266717
Matsuyama, Ehime, Japan, 790-8524
Actively Recruiting
12
Uwajima City Hospital /ID# 273444
Uwajima, Ehime, Japan, 798-0061
Actively Recruiting
13
Fukuoka University Chikushi Hospital /ID# 262686
Chikushino-shi, Fukuoka, Japan, 818-8502
Actively Recruiting
14
Sakemi clinic /ID# 275589
Fukuoka, Fukuoka, Japan, 813-0003
Actively Recruiting
15
Tobata Kyoritsu Hospital /ID# 273558
Kitakyushu, Fukuoka, Japan, 804-0093
Actively Recruiting
16
Steel Memorial Yahata Hospital /ID# 272713
Kitakyushu, Fukuoka, Japan, 805-0050
Actively Recruiting
17
Kitakyushu Municipal Medical Center /ID# 276257
Kitakyushu-shi, Fukuoka, Japan, 802-0077
Actively Recruiting
18
Hidaka Colon Proctology Clinic /ID# 268867
Kurume, Fukuoka, Japan, 839-0809
Actively Recruiting
19
Hakuai Clinic /ID# 261876
Kurume-shi, Fukuoka, Japan, 839-0863
Actively Recruiting
20
Ashiya Central Hospital /ID# 275324
Onga-gun, Fukuoka, Japan, 807-0101
Actively Recruiting
21
Southern Tohoku General Hospital /ID# 270447
Kōriyama, Fukushima, Japan, 963-8563
Actively Recruiting
22
Gifu University Hospital /ID# 266711
Gifu, Gifu, Japan, 501-1194
Actively Recruiting
23
Sakura Clinic /ID# 268344
Kakamigahara-shi, Gifu, Japan, 504-0907
Actively Recruiting
24
National Hospital Organization Fukuyama Medical Center /ID# 261873
Fukuyama-shi, Hiroshima, Japan, 720-8520
Actively Recruiting
25
JA Hiroshima General Hospital /ID# 264432
Hatsukaichi, Hiroshima, Japan, 738-8503
Actively Recruiting
26
Kaisei Clinic /ID# 261883
Hiroshima, Hiroshima, Japan, 730-0017
Actively Recruiting
27
Sapporo Ibd Clinic /ID# 281896
Sapporo, Hokkaido, Japan, 064-0919
Actively Recruiting
28
Ako-City Hospital /ID# 271276
Ako, Hyōgo, Japan, 678-0232
Actively Recruiting
29
Himeji Chuo Hospital /ID# 272714
Himeji, Hyōgo, Japan, 672-8501
Actively Recruiting
30
Hyogo Prefectural Harima-Himeji General Medical Center /ID# 274528
Himeji-shi, Hyōgo, Japan, 670-0836
Actively Recruiting
31
Itami City Hospital /ID# 276258
Itami, Hyōgo, Japan, 664-8540
Actively Recruiting
32
Aoyama Clinic /ID# 262658
Kobe, Hyōgo, Japan, 650-0015
Actively Recruiting
33
Kobe City Medical Center General Hospital /ID# 270950
Kobe, Hyōgo, Japan, 650-0047
Actively Recruiting
34
Hyogo Medical University Hospital /ID# 267383
Nishinomiya-shi, Hyōgo, Japan, 663-8501
Actively Recruiting
35
Kita-Harima Medical Center /ID# 276256
Ono, Hyōgo, Japan, 675-1327
Actively Recruiting
36
Tsukuba Endoscopy clinic /ID# 261880
Tsukuba, Ibaraki, Japan, 305-0821
Actively Recruiting
37
National Hospital Organization Kanazawa Medical Center /ID# 268820
Kanazawa, Ishikawa-ken, Japan, 920-8650
Actively Recruiting
38
Takamatsu Red Cross Hospital /ID# 268823
Takamatsu, Kagawa-ken, Japan, 760-0017
Actively Recruiting
39
Maeda Hospital /ID# 275554
Takamatsu, Kagawa-ken, Japan, 761-8054
Actively Recruiting
40
Kagoshima IBD Gastroenterology Clinic /ID# 265505
Kagoshima, Kagoshima-ken, Japan, 892-0843
Actively Recruiting
41
Tokai University Hospital /ID# 270949
Isehara, Kanagawa, Japan, 259-1193
Actively Recruiting
42
Gokeikai Ofuna Chuo Hospital /ID# 262649
Kamakura-shi, Kanagawa, Japan, 247-0056
Actively Recruiting
43
Shimizuogimachi Clinic /ID# 276278
Odawara-shi, Kanagawa, Japan, 250-0001
Actively Recruiting
44
Kitasato University Hospital /ID# 276524
Sagamihara-shi, Kanagawa, Japan, 252-0375
Actively Recruiting
45
Matsushima Hospital /ID# 276486
Yokohama, Kanagawa, Japan, 220-0041
Actively Recruiting
46
Yokohama Municipal Citizen's Hospital /ID# 267375
Yokohama, Kanagawa, Japan, 221-0855
Actively Recruiting
47
Inoue Gastroenterology Clinic /ID# 275555
Yokohama, Kanagawa, Japan, 223-0053
Actively Recruiting
48
Saiseikai Yokohama Tobu Hospital /ID# 264186
Yokohama, Kanagawa, Japan, 230-0012
Actively Recruiting
49
Chikamori Hospital /ID# 267382
Kochi, Kochi, Japan, 780-8522
Actively Recruiting
50
Coloproctology Center Takano Hospital /ID# 268868
Kumamoto, Kumamoto, Japan, 862-0971
Actively Recruiting
51
Japanese Red Cross Kyoto Daiichi Hosital /ID# 262660
Kyoto, Kyoto, Japan, 605-0981
Actively Recruiting
52
National Hospital Organization Kyoto Medical Center /ID# 265461
Kyoto, Kyoto, Japan, 612-8555
Actively Recruiting
53
Mie University Hospital /ID# 262656
Tsu, Mie-ken, Japan, 514-8507
Actively Recruiting
54
Yokkaichi Hazu Medical Center /ID# 260140
Yokkaichi-shi, Mie-ken, Japan, 510-0016
Actively Recruiting
55
Nagano Municipal Hospital /ID# 262627
Nagano, Nagano, Japan, 3818551
Actively Recruiting
56
Honda Internal Medicine and Endoscopy Clinic /ID# 275628
Nagasaki, Nagasaki, Japan, 850-0058
Actively Recruiting
57
Ishida Clinic of IBD and Gastroenterology /ID# 261884
Ōita, Oita Prefecture, Japan, 870-0823
Actively Recruiting
58
University of the Ryukyus Hospital /ID# 264430
Ginowan-shi, Okinawa, Japan, 901-2725
Actively Recruiting
59
Naha City Hospital /ID# 261875
Naha, Okinawa, Japan, 902-0061
Actively Recruiting
60
Seshimo Gastroy & Procto Clinic /ID# 271658
Ibaraki-shi, Osaka, Japan, 567-0882
Actively Recruiting
61
Moriguchi Keijinkai Hospital /ID# 268821
Moriguchi, Osaka, Japan, 570-0013
Actively Recruiting
62
Kinshukai Infusion Clinic /ID# 261332
Osaka, Osaka, Japan, 530-0011
Actively Recruiting
63
National Hospital Organization Osaka National Hospital /ID# 264230
Osaka, Osaka, Japan, 540-0006
Actively Recruiting
64
Osaka Metropolitan University Hospital /ID# 273559
Osaka, Osaka, Japan, 545-8586
Actively Recruiting
65
Tane General Hospital /ID# 268871
Osaka, Osaka, Japan, 550-0025
Actively Recruiting
66
Osaka Rosai Hospital /ID# 267379
Sakai, Osaka, Japan, 591-8025
Actively Recruiting
67
Fujita Gastroenterology Hospital /ID# 275410
Takatsuki, Osaka, Japan, 569-0086
Actively Recruiting
68
Ohmori Toshihide Gastrointestinal Clinic /ID# 276192
Ageo, Saitama, Japan, 362-0075
Actively Recruiting
69
Saitama Medical Center /ID# 270948
Kawagoe, Saitama, Japan, 350-8550
Actively Recruiting
70
Tokitokai Tokito clinic /ID# 262661
Saitama-shi, Saitama, Japan, 336-0963
Actively Recruiting
71
Tokorozawa Proctogic Hospital /ID# 268870
Tokorozawa, Saitama, Japan, 359-1141
Actively Recruiting
72
Kato Clinic /ID# 262650
Hamamatsu, Shizuoka, Japan, 432-8061
Actively Recruiting
73
Shizuoka Aoi Clinic /ID# 267376
Shizuoka, Shizuoka, Japan, 420-0881
Actively Recruiting
74
Saigusa Clinic Of Coloproctolo /ID# 275627
Sizuoka-shi, Shizuoka, Japan, 420-0859
Actively Recruiting
75
NHO Shizuoka Medical Center /ID# 275551
Sunto-gun, Shizuoka, Japan, 411-8611
Actively Recruiting
76
Dokkyo Medical University Hospital /ID# 266710
Mibu, Tochigi, Japan, 321-0293
Actively Recruiting
77
Saiseikai Utsunomiya Hospital /ID# 261878
Utsunomiya, Tochigi, Japan, 321-0974
Actively Recruiting
78
Juntendo University Hospital /ID# 265452
Bunkyo-ku, Tokyo, Japan, 113-8431
Actively Recruiting
79
Ginza Central Clinic /ID# 261881
Chuo-ku, Tokyo, Japan, 104-0061
Actively Recruiting
80
Koganei Tsurukame Clinic /ID# 271660
Koganei-shi, Tokyo, Japan, 184-0004
Actively Recruiting
81
Kitasato University Kitasato Institute Hospital /ID# 268345
Minato-ku, Tokyo, Japan, 108-8642
Actively Recruiting
82
Ohori IBD Clinic /ID# 261882
Setagaya-ku, Tokyo, Japan, 155-0032
Actively Recruiting
83
Shinjuku Tsurukame Clinic /ID# 276485
Shibuya-ku, Tokyo, Japan, 151-0053
Actively Recruiting
84
Tokyo Medical University Hospital /ID# 262683
Shinjuku-ku, Tokyo, Japan, 160-0023
Actively Recruiting
85
Tokyo Women's Medical University Hospital /ID# 274527
Shinjuku-ku, Tokyo, Japan, 162-8666
Actively Recruiting
86
Fraternity Memorial Hospital /ID# 274976
Sumida-ku, Tokyo, Japan, 130-8587
Actively Recruiting
87
Yokota Memorial Hospital /ID# 266714
Toyama, Toyama, Japan, 939-8085
Actively Recruiting
88
Japanese Red Cross Wakayama Medical Center /ID# 268822
Wakayama, Wakayama, Japan, 640-8558
Actively Recruiting
89
Wakayama Medical University Hospital /ID# 262685
Wakayama, Wakayama, Japan, 641-8510
Actively Recruiting
90
Sentohill Hospital /ID# 268869
Ube, Yamaguchi, Japan, 755-0155
Actively Recruiting
91
Yamanashi Prefectural Central Hospital /ID# 274526
Kofu, Yamanashi, Japan, 400-0027
Actively Recruiting
92
Fukuiken Saiseikai Hospital /ID# 274835
Fukui, Japan, 918-8235
Actively Recruiting
93
Fukushima Red Cross Hospital /ID# 275322
Fukushima, Japan, 960-8530
Actively Recruiting
94
Japanease Red Cross Society Himeji Hospital /ID# 275590
Himeji, Japan, 670-8540
Actively Recruiting
95
Kuniyoshi Hospital /ID# 271878
Kochi, Japan, 780-0901
Actively Recruiting
96
Saga-Ken Medical Centre Koseikan /ID# 274957
Saga, Japan, 840-8571
Actively Recruiting
97
Saitama City Hospital /ID# 266716
Saitama, Japan, 336-8522
Actively Recruiting
98
Sapporo Kosei General Hospital /ID# 267374
Sapporo, Japan, 060-0033
Actively Recruiting
99
Tokyo Yamate Medical Center /ID# 275591
Tokyo, Japan, 169-0073
Actively Recruiting
100
Teikyo University Hospital /ID# 274525
Tokyo, Japan, 173-8605
Actively Recruiting
101
Teikyo University Hospital /ID# 274977
Tokyo, Japan, 173-8605
Actively Recruiting
102
Municipal Toyonaka Hospital /ID# 266712
Toyonaka, Japan, 560-0055
Actively Recruiting
103
Yamagata Prefectural Central Hospital - Yamagata /ID# 268819
Yamagata, Japan, 990-2292
Actively Recruiting
104
Yamaguchi Red Cross Hospital /ID# 267381
Yamaguchi, Japan, 753-8519
Actively Recruiting
Research Team
A
AbbVie GK Clinical Trial Registration Desk
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here