Actively Recruiting

Age: 18Years +
All Genders
NCT04338204

Observational Study To Assess The Effectiveness and Treatment Adherence Of Tofacitinib of Ulcerative Colitis In Clinical Practice In Sweden

Led by Pfizer · Updated on 2026-03-13

120

Participants Needed

17

Research Sites

289 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective observational study using data from an existing, ongoing National Swedish registry (SWIBREG). This study is designed to assess the effectiveness and treatment adherence of tofacitinib on clinical disease activity parameters in patients with ulcerative colitis in Swedish clinical practice. The study will also assess treatment adherence of tofacitinib using the Swedish Prescribed Drug Register.

CONDITIONS

Official Title

Observational Study To Assess The Effectiveness and Treatment Adherence Of Tofacitinib of Ulcerative Colitis In Clinical Practice In Sweden

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • The patient is prescribed tofacitinib according to clinical practice and guidelines, not decided by the study protocol.
  • The patient has signed informed consent allowing data collection from SWIBREG.
  • Patients must be 18 years old or older.
  • The patient has active ulcerative colitis confirmed by fecal calprotectin >250 mg/kg or an endoscopic Mayo subscore 2 not more than 4 weeks before starting tofacitinib treatment.
Not Eligible

You will not qualify if you...

  • The patient is enrolled in a clinical trial where ulcerative colitis treatment is controlled by the study protocol.
  • Patients with any contraindications to tofacitinib as per the latest product information.
  • The physician considers the patient unsuitable for participation in the study.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 17 locations

1

Ulf Eriksson

Alingsås, Sweden, SE-441 33

Active, Not Recruiting

2

Medicinkliniken, Södra Älvsborgs Sjukhus Borås, Brämhultsvägen 53

Borås, Sweden

Active, Not Recruiting

3

Gävle Hospital

Gävle, Sweden, 80324

Active, Not Recruiting

4

SU/Sahlgrenska, Gastroenterologi & Hepatologi

Gothenburg, Sweden, Göteborg

Active, Not Recruiting

5

Medicinkliniken, Länssjukhuset Ryhov, Sjukhusgatan

Jönköping, Sweden, 55185

Active, Not Recruiting

6

Daniel Molin

Kristianstad, Sweden, 29185

Actively Recruiting

7

Shiprock Consulting AB,

Lidingö, Sweden

Active, Not Recruiting

8

Mag-Tarmmedicinska kliniken, Universitetssjukhuset i Linköping

Linköping, Sweden, 58185

Active, Not Recruiting

9

Region skåne, Skånes Universitetssjukhus

Malmö, Sweden, 20501

Active, Not Recruiting

10

Medicinmottagning 4, Medicinska Kliniken, Universitetssjukhuset Örebro

Örebro, Sweden, 70185

Active, Not Recruiting

11

Stockholm Gastro Center

Stockholm, Sweden, 11486

Active, Not Recruiting

12

Ersta Sjukhus, Medicinkliniken, Fjällgatan 44

Stockholm, Sweden, 11691

Active, Not Recruiting

13

Karolinska Universitetssjukhuset i Solna, Eugeniavägen 3, B4-09,

Stockholm, Sweden, 17176

Active, Not Recruiting

14

Danderyds Hospital

Stockholm, Sweden, 18257

Active, Not Recruiting

15

Medicinkliniken, Umeås Universitetssjukhus

Umeå, Sweden, 50985

Active, Not Recruiting

16

Specialmedicin, Akademiska Sjukhuset, Sjukhusvägen ing 40

Uppsala, Sweden, 75185

Active, Not Recruiting

17

Medicinmottagningen gastroenterologi, Västmanlands sjukhus

Västerås, Sweden, 72189

Active, Not Recruiting

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Research Team

P

Pfizer CT.gov Call Center

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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