Actively Recruiting

Age: 18Years +
All Genders
NCT07075445

Observational Study to Describe Health-Related Quality of Life and Measure Disease Burden Among Patients With Long QT Syndrome Types (LQTS) 2 and 3

Led by Thryv Therapeutics, Inc. · Updated on 2025-11-17

200

Participants Needed

1

Research Sites

57 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a cross-sectional observational study designed to assess the disease burden and quality of life in individuals with LQTS 2 and 3. Each participant will answer each patient-reported outcome questionnaire only once over a 6-month period. The study will enroll up to 200 participants.

CONDITIONS

Official Title

Observational Study to Describe Health-Related Quality of Life and Measure Disease Burden Among Patients With Long QT Syndrome Types (LQTS) 2 and 3

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must be 18 years or older and speak English.
  • Willing to provide written informed consent.
  • Confirmed genetic diagnosis of LQTS type 2 or 3 by genetic testing or physician's letter.
  • Documented QTc value of 480 ms or higher within the past year by ECG or physician's letter.
  • Able to operate a smartphone and companion watch (Apple iPhone and Apple Watch).
  • Limited to 50 participants with QTc between 480 and 500 ms.
Not Eligible

You will not qualify if you...

  • Currently participating in another clinical trial involving a drug or device.
  • Unwilling to use an iPhone or Apple Watch for the study duration.
  • Known diagnosis of Brugada Syndrome.
  • Unwilling to comply with study procedures.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

East Carolina University

Greenville, North Carolina, United States, 27858

Actively Recruiting

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Research Team

S

Study Coordinator

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Observational Study to Describe Health-Related Quality of Life and Measure Disease Burden Among Patients With Long QT Syndrome Types (LQTS) 2 and 3 | DecenTrialz