Actively Recruiting
An Observational Study to Evaluate Effectiveness and Safety of Upadacitinib in Chinese Adult Participants With Moderate to Severely Active Ulcerative Colitis (UC)
Led by AbbVie · Updated on 2025-11-26
80
Participants Needed
3
Research Sites
85 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Ulcerative colitis (UC) is a chronic, relapsing, and incurable inflammatory disease of the large intestine. The hallmark clinical symptoms include bloody diarrhea associated with rectal urgency and tenesmus.. This study will assess how effective upadacitinib is in treating UC within a Chinese population. Upadacitinib is an approved drug for treating UC. Approximately 80 adult participants, who have been prescribed upadacitinib for UC by their physician in accordance with local label, will be enrolled in China. Upadacitinib will be administered in accordance with the terms of the local marketing authorization, and treatment of participants will be determined solely by the investigator. Participants in the study will be followed for up to 1 year. There will be no additional burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic and only data which are routinely collected during a regular visit will be utilized for this study.
CONDITIONS
Official Title
An Observational Study to Evaluate Effectiveness and Safety of Upadacitinib in Chinese Adult Participants With Moderate to Severely Active Ulcerative Colitis (UC)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Chinese adults aged 18 years or older
- Diagnosed with moderate to severely active ulcerative colitis
- Prescribed upadacitinib by treating physicians following local label
- Provided written authorization to use personal and health data before study entry
You will not qualify if you...
- Currently participating in any interventional clinical trials
- Have any contraindication to upadacitinib as listed in the local China label
- Unwilling or unable to comply with study requirements, including completing patient questionnaires
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
The First Affiliated Hospital, Sun-Yat Sen University /ID# 272997
Guangzhou, Guangdong, China, 510080
Actively Recruiting
2
The Sixth Affiliated Hospital of Sun Yat-sen University /ID# 274753
Guangzhou, Guangdong, China, 510655
Actively Recruiting
3
The Second Affiliated Hospital Of Zhengzhou University /ID# 274754
Zhengzhou, Henan, China, 450014
Actively Recruiting
Research Team
Y
Yuting Xie
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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