Actively Recruiting
An Observational Study of Menopausal Symptom in Patients With Gynecological Malignancy After Oophorectomy
Led by Anhui Provincial Hospital · Updated on 2024-03-07
490
Participants Needed
1
Research Sites
526 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Through long-term dynamic monitoring of gynecologic malignant tumor patients undergoing early menopause after ovaries resection in our center, we explored the changes in menopausal symptoms and bone health status of this population, and studied the effects of platinum combined chemotherapy drugs on menopausal symptoms and bone loss in gynecologic malignant tumor patients. To find the optimal time point and effective regimen for MHT in gynecologic malignancies undergoing surgical menopause, and to provide guidance for osteoporosis screening and prevention strategies in women with gynecologic cancer.
CONDITIONS
Official Title
An Observational Study of Menopausal Symptom in Patients With Gynecological Malignancy After Oophorectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Premenopausal women with gynecological malignancies aged 18-55 years old
- Diagnosed with endometrial cancer, cervical cancer, or epithelial ovarian cancer
- Received standard surgery and treatment for their tumor
- Underwent bilateral ovary removal surgery
- Voluntarily agree to participate and able to complete long-term follow-up
You will not qualify if you...
- Women who have reached natural menopause (no menstruation for 12 months after age 40) or have AMH less than 0.2 ng/ml or FSH greater than 40 mIU/ml confirmed twice within one month
- Diagnosed with other tumors within the last 2 years and currently undergoing radiotherapy, chemotherapy, or hormone therapy
- Diagnosed with immunodeficiency diseases, active hepatitis B or C, or active tuberculosis
- Have serious organ diseases preventing study follow-up
- Long-term use of hormonal drugs for rheumatic diseases such as glucocorticoids
- Previously received pelvic or abdominal radiotherapy
- ECOG performance status score of 3 or higher
- Unwilling or unable to provide informed consent or participate in follow-up interviews
AI-Screening
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Trial Site Locations
Total: 1 location
1
Anhui Provincal Hospital
Hefei, Anhui, China
Actively Recruiting
Research Team
Y
Ying Zhou, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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