Observational Study on Menopausal Symptoms and Bone Health in Women Aged 18-55 With Gynecological Cancers After Ovary Removal

What this Trial Is About

This research aims to monitor women with gynecologic cancers who experience early menopause after having their ovaries removed. The study looks at how menopausal symptoms and bone health change over time in these patients. It also examines how platinum-based chemotherapy drugs may affect menopausal symptoms and bone loss. The goal is to identify the best timing and effective hormone therapy programs for these women and to guide osteoporosis screening and prevention strategies. This is an observational study where patients receive no specific intervention as part of the trial. Researchers will follow these women after their surgery, tracking changes in their bone mineral density and symptoms related to menopause using various scales. Patients are observed over multiple time points up to 36 months post-operation to gather comprehensive data about their health status. Participants will undergo regular assessments including bone mineral density tests and evaluations of menopausal symptoms, mood, sleep quality, and osteoporosis risk at intervals from 1 month to 3 years after surgery. The study also tracks longer-term outcomes like overall survival and progression-free survival over 5 years. This thorough monitoring helps researchers understand the effects of surgery and chemotherapy on these patients quality of life and bone health.

An Observational Study of Menopausal Symptom in Patients With Gynecological Malignancy After Oophorectomy