Actively Recruiting

Age: 18Years +
All Genders
NCT06376448

An Observational Study Using Novel Questionnaire to Characterize Cough Phenotypes in Patients With Chronic Cough

Led by Hull University Teaching Hospitals NHS Trust · Updated on 2025-08-01

60

Participants Needed

1

Research Sites

163 weeks

Total Duration

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AI-Summary

What this Trial Is About

Cough has previously been described by the type of cough you have ie such as wet, dry, and chesty, and also by its features such as how often you are coughing its,intensity, and severity, but never has the varying patterns of cough been studied in any detail and it could be that the pattern of the cough is closely related to patient-perceived intensity, frequency and most importantly severity. Cough is a symptom and like any other symptom (such as pain) the severity of it can only be gauged by the patient experiencing it. We have created a one-page brand newl questionnaire that shows 4 distinct cough patterns that we believe exist and an empty field designed so that patients can record a pattern of cough they experience which is not already a choice on the questionnaire. The questionnaire also records patients' experience of how frequent, and intense, the cough is, and how it disrupts their lives, on a 1-10 scale (Visual analogue scale), the sum of these scores is collated and this gives us a severity score. The first phase of the project is to determine whether 30 Chronic cough patients understand the questionnaire, and are able to complete it with little direction, and if the cough patterns we identified encompassed all pattern types. second part of the study is to look at how repeatable the questionnaire is when completed over a 6 week period.

CONDITIONS

Official Title

An Observational Study Using Novel Questionnaire to Characterize Cough Phenotypes in Patients With Chronic Cough

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female patients older than 18 years of age
  • Current cough lasting at least 8 weeks
  • Clear chest X-ray within the previous 2 years
  • Non-smoker
  • Able to understand and follow study instructions and sign consent forms
  • Good understanding of written and spoken English
Not Eligible

You will not qualify if you...

  • Respiratory tract infection within the last 4 weeks
  • Current smokers or ex-smokers with less than 6 months abstinence before the study
  • Any significant or unstable medical or psychiatric condition that affects safe participation
  • Participation in a clinical trial with an investigational drug within 30 days or 5 half-lives before the study visit
  • Any other reason the investigator considers the subject should not participate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Redspiratory Medicine, First Floor, Daisy Building, Castle Hill Hospital

Cottingham, East Yorkshiure, United Kingdom, HU16 5JQ

Actively Recruiting

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Research Team

C

Caroline Wright, BSc

CONTACT

R

Rachel Thompson

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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