Actively Recruiting

Age: 18Years +
All Genders
NCT05113407

Observatory on the Use of the Shockwave Medical C2 Coronary Lithotripsy System in the General Population in France.

Led by French Cardiology Society · Updated on 2025-02-10

500

Participants Needed

1

Research Sites

315 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Coronary calcified lesions will have an increasing impact in the daily practice of coronary angioplasty, considering the epidemiological explosion of factors favoring coronary calcifications, first of all diabetes. Moreover, calcified lesions are underestimated in angiography and associated with an increase in angiographic complications, as well as with a worse clinical prognosis. The usual techniques for the preparation of calcified plaque, in particular rotary atherectomy, have a low penetration rate in France (3% of procedures) and are associated with an increase in per-procedural complications without clinical evidence of effectiveness4. A new device has been developed by Schockwave Medical Inc. for the treatment of calcified lesions to facilitate stent delivery: the C2 Shockwave Medical® Coronary Lithotripsy System (IVL), Inc. This system uses the principle of lithotripsy to induce microfractures in the calcified plaque prior to low-pressure balloon dilatation. The objective of the study is to evaluate the safety and performance of the C2 Shockwave Medical® (IVL), Inc. coronary lithotripsy system in coronary angioplasty in the general population in France.

CONDITIONS

Official Title

Observatory on the Use of the Shockwave Medical C2 Coronary Lithotripsy System in the General Population in France.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient over 18 years old
  • Patient affiliated to the National Health Insurance System
  • Patient undergoing coronary angioplasty using the Shockwave Medical C2 Coronary Lithotripsy System
  • For stent malexpansion cases, defined by angiography showing malexpansion >30% or imaging with minimal stent area <4.5 mm2 or ratio of minimal stent area to reference segment <0.8
  • Patient willing to participate in the registry
Not Eligible

You will not qualify if you...

  • Patient under 18 years of age
  • Pregnant or breastfeeding patient
  • Patient refusing to participate or unable to give informed consent due to guardianship or legal reasons

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Clinique Pasteur

Toulouse, France

Actively Recruiting

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Research Team

B

Benjamin HONTON

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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