Actively Recruiting
Obstructive Sleep Apnea Treatment From Acute to Chronic Phase of Stroke
Led by Hospital das Clínicas de Ribeirão Preto · Updated on 2025-07-01
425
Participants Needed
1
Research Sites
365 weeks
Total Duration
On this page
Sponsors
H
Hospital das Clínicas de Ribeirão Preto
Lead Sponsor
F
Fundação de Amparo à Pesquisa do Estado de São Paulo
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study aims to evaluate whether early treatment of obstructive sleep apnea with continuous positive airway pressure in ischemic stroke patients has a favorable effect on functional recovery.
CONDITIONS
Official Title
Obstructive Sleep Apnea Treatment From Acute to Chronic Phase of Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Supratentorial non-lacunar ischemic stroke, including anterior, middle, and posterior cerebral artery territories
- Aged 18 to 80 years
- Symptom onset or symptom recognition to admission less than 12 hours
- NIHSS score greater than or equal to 4 and less than or equal to 20 at enrollment
- Signed informed consent form obtained from the participant or their legal representative
You will not qualify if you...
- Prior stroke
- Previous diagnosis of obstructive sleep apnea with current CPAP use or previously failed CPAP
- Pre-stroke disability with modified Rankin Scale greater than 1
- Coma or stupor
- Orotracheal intubation
- Clinical instability or severe pre-existing illness such as heart failure, oxygen-dependent COPD, renal or hepatic failure
- Psychomotor agitation
- High likelihood of neurosurgical intervention within the first 48 hours
- Oxygen therapy greater than 2 liters per minute
- Known severe neurological diseases including dementia, Parkinson's disease, multiple sclerosis, or other neurodegenerative conditions
- Chronic alcohol or drug use with high risk of withdrawal during hospitalization
- Pregnant or suspected pregnant women
- Inability to complete follow-up for any reason
- Any contraindication to CPAP use
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital das Clínicas, Ribeirão Preto Medical School, University of São Paulo
Ribeirão Preto, São Paulo, Brazil, 14015-130
Actively Recruiting
Research Team
M
Millene Camilo, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
5
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