Collecting Tumor and Normal Tissue Samples From Patients Undergoing Surgery or Biopsy for Solid Tumors

What this Trial Is About

Recent advances in cancer research have led to new therapies, and ongoing studies seek to discover more by collecting tissue samples from solid tumors. This research focuses on participants aged 2 years and older who have premalignant, primary, or metastatic solid tumors and are scheduled for surgery or biopsy as part of their medical care. The goal is to identify new molecular and biological targets to aid future cancer treatments by studying these tissue samples. Participants will have blood samples taken before their procedure, and some may undergo leukapheresis, a process that removes white blood cells from the blood. During surgery or biopsy, pieces of tumor and nearby normal tissue will be collected for research, while the remainder will be sent for laboratory analysis. After the procedure, participants will return about six weeks later for a routine checkup, with some possibly needing additional follow-up visits. Throughout the study, researchers will collect biological samples and detailed medical data related to the participants tumors and surgical outcomes. Assessments include blood tests, tissue analysis, and follow-up evaluations to track safety and quality of care. Participation involves regular clinic visits around the time of surgery and afterward, with data collected to support the identification of potential new cancer therapies and improve surgical practices.

Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer