Actively Recruiting
Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer
Led by National Cancer Institute (NCI) · Updated on 2026-05-07
1800
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: \- Recent advances in cancer research have led to new therapies to treat the disease. It is important to continue these advances and discover new ones. To do that, researchers need tissue samples from solid tumors. This study will collect such samples from people already scheduled to have a procedure at the National Institutes of Health Clinical Center (NIHCC). Objectives: \- To collect tissue samples for use in studying new ways to treat tumors. Eligibility: * Adults 18 years and older, with a precancerous or cancerous solid tumor who are scheduled to have surgery or a biopsy at the NIHCC. * Children under the age of 18 but who are older than 2 years of age are eligible to be enrolled on the research sample collection portion of this study if they will have a biopsy or surgery as part of their medical care. Design: * Before their procedure, participants will have a small blood sample taken. * Some participants will undergo leukapheresis. In this procedure, blood is removed through a tube in one arm and circulated through a machine that removes white blood cells. The blood, minus the white blood cells, is returned through a tube in the other arm. The procedure takes 3-4 hours. * For all participants, during the surgery or biopsy, pieces of the tumor and pieces of normal tissue near it will be removed for this study. The rest of the tumor or precancerous growth will be sent to a lab for analysis. * Participants will return to the clinic about 6 weeks after the operation for a routine checkup. Some may have to return for additional follow-up.
CONDITIONS
Official Title
Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must be 2 years of age or older.
- Participants aged 2 to under 18 years may only participate if tissue collection occurs during clinically indicated surgery and does not add risk.
- Participants must have premalignant, primary, or metastatic solid tumors based on clinical, radiographic, biochemical, genetic, or histological evidence requiring surgery or biopsy.
- Participants without solid tumors undergoing diagnostic, preventative, or therapeutic intervention where surgical quality and safety data are collected.
- Participants must have acceptable laboratory and physical exam results prior to surgery or biopsy.
- Participants must be planning to undergo surgery or biopsy as part of their normal treatment.
- Participants or their legal representatives must be able to understand and sign informed consent.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
C
Cathleen E Hannah, C.R.N.P.
CONTACT
J
Jonathan M Hernandez, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here