Temporomandibular disorders: the habitual chewing side syndrome.
Urbano Santana-Mora, José López-Cedrún, María J Mora...
https://pubmed.ncbi.nlm.nih.gov/23593156Actively Recruiting
Age: 18Years - 85Years
All Genders
ID07445516
Physiologically Oriented Occlusal Equilibration Versus Sham Therapy for Chronic Temporomandibular Disorders: 10 Years Post-Trial Follow-Up
Led by Urbano Santana Penin · Updated on 2026-03-04
110
Participants Needed
2
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Chronic temporomandibular disorders (TMDs) affect the muscles used for chewing, the jaw joints, and nearby structures. The causes of TMDs are often unclear and involve multiple factors. While many patients find relief with conservative treatments or no active intervention, about 3% develop persistent TMD pain, causing significant personal suffering and social and economic challenges. Researchers are studying the long-term effectiveness of Physiologically Oriented Occlusal Equilibration (POOE), a treatment used since 1985 at the University of Santiago de Compostela, which aims to correct chewing patterns and protect the jaw joints from overload. This single-blind observational study compares POOE with sham therapy to evaluate pain reduction and disease improvement over at least 10 years. This study observes patients who previously underwent treatment for chronic TMDs at the University of Santiago de Compostela. Participants either received POOE therapy or a simulated sham therapy. The study does not apply new treatments but assesses participants at a single time point to measure current TMD status. Diagnostic procedures include oral examinations and movement recordings following standardized criteria. Medical records are reviewed with participant consent to assess changes from before treatment to present. Participants will attend one study visit involving a detailed examination for TMD symptoms and jaw function. Researchers will measure pain intensity, maximum mouth opening, psychological distress, and jaw movement angles, comparing these with pretreatment records. The main outcome is the difference in pain levels between groups after about 10 years. Safety and other health factors are monitored through questionnaires. The study's total duration is a single visit with data collected from past treatments and current assessments.
CONDITIONS
Brief Title
Occlusal Equilibration vs. Sham Therapies for TMDs: Post-Trial Follow-up (OEST)
Who Can Participate
Age: 18Years - 85Years
All Genders
Eligibility Criteria
You may qualify if you...
- Previous occlusal equilibration treatment for TMD pain at the University of Santiago
- Diagnosed with joint and/or muscle TMD pain according to DC/TMD criteria
- Aged between 18 and 85 years
- Completely dentate with normal or adequately restored occlusion (fixed crowns or bridges allowed)
- Reported significant TMD pain before treatment (VAS/NRS score 4-9 on a 0-10 scale)
- Have actively sought treatment and been referred to the University or Hospital service
- Have undergone at least 6 months of prior conservative therapy
You will not qualify if you...
- Psychosis, major depression, substance abuse, or cognitive impairment
- Addiction to opioid (morphine-derivative) medications
- Ongoing litigation or disability claims related to chronic pain
- Background as a dental professional
- Orthodontic treatment within the last 2 years
- Severe tooth mobility (grade 3)
- Other pain conditions that are indistinguishable from or more severe than TMD pain
- Inability to achieve equilibration with minimally invasive occlusal adjustment due to specific dental discrepancies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - Single time point
Participants undergo diagnostic procedures to assess current temporomandibular disorders (TMDs), including extra- and intraoral examinations, dynamic recording of mandibular and condylar movements, and tests recommended by DC/TMD criteria.
1 visit (in-person)
Long-term Monitoring
Duration - Up to 10 years post-treatment
Participants who previously received occlusal equilibration or sham therapy are observed for long-term effects on pain intensity and jaw function over several years without any new intervention.
1 visit (in-person) at 10 years post-treatment
Trial Site Locations
Total: 2 locations
1
Universidad de Santiago de Compostela
Santiago de Compostela, A Coruña, Spain, 15782
Actively Recruiting
2
Urbano Santana Penín
Santiago de Compostela, A Coruña, Spain, 15782
Enrolling by Invitation
Loading map...
Research Team
U
URBANO SANTANA PENIN, Prof.
M
Marcos Almeida Cerreda, Officer
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Published Research Related To This Trial
Asymmetry of dental or joint anatomy or impaired chewing function contribute to chronic temporomandibular joint disorders.
Urbano Santana-Mora, José López-Cedrún, Juán Suárez-Quintanilla...
https://pubmed.ncbi.nlm.nih.gov/34186201Remodeling dental anatomy vs sham therapy for chronic temporomandibular disorders. A placebo-controlled randomized clinical trial.
Urbano Santana-Penín, Urbano Santana-Mora, Alicia López-Solache...
https://pubmed.ncbi.nlm.nih.gov/37302432