Amblyopia Treatment Study Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia

Led by Jaeb Center for Health Research · Updated on 2014-03-06

419

Participants Needed

Research Sites

613 weeks

Total Duration

AI-Summary

What this Trial Is About

* To determine whether the success rate with drug treatment (atropine) of amblyopia due to strabismus or anisometropia in patients less than 7 years old is equivalent to the success rate with occlusion (patching) therapy * To develop more precise estimates of the success rates of amblyopia treatment * To identify factors that may be associated with successful treatment of amblyopia * To collect data on the course of treated amblyopia to provide more precise estimates of treatment effects than are now available Extended Follow up of Study Patients * Primary: To determine the long-term visual acuity outcome at age 10 years and at age 15 years in patients diagnosed with amblyopia before age 7 years. * Secondary: To determine whether the long-term visual acuity outcome at age 10 years and at age 15 years differs between patients who received patching followed by best clinical care and patients who received atropine followed by best clinical care

CONDITIONS

Brief Title

Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia

Who Can Participate

Age: 0 - 6Years

All Genders

Eligibility Criteria

Inclusion Criteria:

Patients must be 7 years old or younger with amblyopia due to strabismus or anisometropia
Visual acuity in the amblyopic eye must be between 20/40 and 20/100
Visual acuity in the sound eye or 20/40 or better
At least 3 lines of acuity difference between the two eyes

Exclusion Criteria:

More than two months of amblyopia therapy in the past two years
Myopia (more than -0.50 D)

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here