Actively Recruiting
OCT Versus Angiography for Culprit Lesion Revascularization in Acute Myocardial Infarction PatiEnts
Led by Chonnam National University Hospital · Updated on 2026-05-08
1500
Participants Needed
18
Research Sites
405 weeks
Total Duration
On this page
Sponsors
C
Chonnam National University Hospital
Lead Sponsor
S
Samsung Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of the study is to compare clinical outcomes between optical coherence tomography-guided versus angiography-guided percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI).
CONDITIONS
Official Title
OCT Versus Angiography for Culprit Lesion Revascularization in Acute Myocardial Infarction PatiEnts
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subject must be at least 19 years of age
- Acute ST-segment elevation myocardial infarction (STEMI) defined as ST-segment elevation ≥0.1 mV in ≥2 contiguous leads or newly developed left bundle-branch block
- Primary percutaneous coronary intervention (PCI) within less than 12 hours after symptom onset for STEMI patients
- Able to understand risks, benefits, and treatment alternatives and provide written informed consent
You will not qualify if you...
- Target lesions not suitable for PCI by operator's decision
- Ostial lesions located in left main vessel or right coronary artery (left main body or distal bifurcation lesions may be enrolled at operator's discretion)
- Creatinine clearance ≤30 ml/min/1.73 m2 and not on dialysis (dialysis-dependent patients eligible regardless of clearance)
- Cardiogenic shock (Killip class IV) at presentation
- Intolerance to Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Heparin, or Everolimus
- Known true anaphylaxis to contrast medium
- Pregnancy or breastfeeding
- Non-cardiac conditions with life expectancy less than 2 years or that risk protocol non-compliance
- Unwillingness or inability to comply with study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 18 locations
1
Kyungpook National University Hospital
Daegu, Daegu, South Korea, 41944
Actively Recruiting
2
Yeungnam University Medical Center
Daegu, Daegu, South Korea, 42415
Actively Recruiting
3
Daegu Catholic University Medical Center
Daegu, Daegu, South Korea, 42472
Actively Recruiting
4
Chonnam National University
Gwangju, Gwangju, South Korea, 61469
Actively Recruiting
5
Wonkwang University Hospital
Iksan, Iksan, South Korea, 54538
Actively Recruiting
6
International St. Mary's Hospital
Incheon, Incheon, South Korea, 22711
Actively Recruiting
7
Jeju National University Hospital
Jeju City, Jeju-do, South Korea, 63241
Actively Recruiting
8
Jeonbuk National University Hospital
Jeonju, Jeonju, South Korea, 54907
Actively Recruiting
9
Gyeongsang National University Hospital
Jinju, Jinju, South Korea, 52727
Actively Recruiting
10
Kyung Hee University Hospital
Seoul, Seoul, South Korea, 02447
Actively Recruiting
11
Samsung Medical Center
Seoul, Seoul, South Korea, 06351
Actively Recruiting
12
Chung-Ang University Hospital
Seoul, Seoul, South Korea, 06973
Actively Recruiting
13
Ewha Womans University Seoul Hospital
Seoul, Seoul, South Korea, 07804
Actively Recruiting
14
Ewha Womans University Mokdong Hospital
Seoul, Seoul, South Korea, 07985
Actively Recruiting
15
Korea University Guro Hospital
Seoul, Seoul, South Korea, 08308
Actively Recruiting
16
St. Carollo Hospital
Suncheon, Suncheon, South Korea, 57931
Actively Recruiting
17
Uijeongbu St Mary's Hospital
Uijeongbu-si, Uijeongbu, South Korea, 11765
Actively Recruiting
18
Ulsan University Hospital
Ulsan, Ulsan, South Korea, 44033
Actively Recruiting
Research Team
S
Seung Hun Lee, MD, PhD
CONTACT
Y
Young Joon Hong, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here