Actively Recruiting
Ocular Blood Flow Imaging for Glaucoma Assessment
Led by University of Maryland, Baltimore · Updated on 2025-03-28
150
Participants Needed
1
Research Sites
213 weeks
Total Duration
On this page
Sponsors
U
University of Maryland, Baltimore
Lead Sponsor
N
National Eye Institute (NEI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to investigate the use of an FDA-cleared retinal blood flow imaging instrument called the XyCAM RI and XyCAM FC (Vasoptic Medical, Inc., Columbia, MD) in glaucoma management. The main question it aims to answer are: * Can the investigators use blood flow to discriminate between eyes with early-stage glaucoma and variable-matched controls? * Can the investigators validate that the XyCAM FC simultaneously captures both stereo fundus photography and ocular blood flow monitoring? Participants will be * measured for their blood pressure, heart rate, height, and weight * dilated with tropicamide * imaged using the XyCAM RI, fundus photography, optical coherence tomography, and standard automated perimetry * imaged using the XyCAM RI while inhaling 100% oxygen through a mask
CONDITIONS
Official Title
Ocular Blood Flow Imaging for Glaucoma Assessment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 and older with binocular vision
- Able to provide informed consent
- Participant is a healthy control OR recommended for glaucoma assessment OR diagnosed with moderate to severe glaucoma in at least one eye as determined by Hodapp Anderson Criteria
You will not qualify if you...
- Significant media opacity such as a visually significant cataract or corneal scar
- Previous ocular surgery except uncomplicated cataract extraction, laser trabeculoplasty (ALT or SLT), or YAG capsulotomy
- Prior ocular disease other than glaucoma
- Anatomically narrow angles or prior adverse reaction to Tropicamide or fluorescein dye
- More than 15 diopters of refractive error
- Female who is pregnant or nursing
- Diabetes mellitus
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Maryland Eye Associates at Redwood
Baltimore, Maryland, United States, 21201
Actively Recruiting
Research Team
O
Osamah J Saeedi, MD, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
3
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