Actively Recruiting
Ocular Complications From Cancer Therapy - Patient Registry and Biobank
Led by University of Maryland, Baltimore · Updated on 2026-03-05
150
Participants Needed
1
Research Sites
307 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to collect data on patients seen at University of Maryland after undergoing cancer therapy. Previous medications, ocular history, medical history, clinical evaluations, surgical procedures and outcomes will be gathered on the patients who consent to participate. Potential subjects will be enrolled from the clinical practice of the investigator at the time of their eye examination visit. A standard of care exam will be performed pertinent to the reason for the visit. In addition to the standard of care exam, certain biological specimens (ocular surface wash, mucocellular material, corneal filaments, impression cytology, and/or blood) will be collected, stored, and analyzed to obtain immunologic, cellular, or molecular mechanistic insights into disease pathogenesis.
CONDITIONS
Official Title
Ocular Complications From Cancer Therapy - Patient Registry and Biobank
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients (greater than 18 years of age)
- Deny a history of eye diseases except cataract, glaucoma, mild dry eye disease, or history of cataract or refractive surgery
- Patients with history of allogenic hematopoietic stem cell transplant (HSCT) or prior cancer therapy including bone marrow transplant, chemotherapy, or immunotherapy (Cancer Therapy Group)
- Patients recruited after HSCT or cancer therapy at ophthalmology appointment (Cancer Therapy Group)
- Patients with no history of cancer or cancer therapy (Control Group)
- Ability to understand and sign the informed consent form approved by the IRB
You will not qualify if you...
- Vulnerable populations such as neonates, children, prisoners, or institutionalized individuals
- Inability or refusal to provide informed consent
- History of ocular surgery or ocular disease except refractive or cataract surgery, mild dry eye disease, or glaucoma
- History of cancer or cancer therapy for Control Group
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Stoler Outpatient Cancer Center at the University of Maryland
Baltimore, Maryland, United States, 21201
Actively Recruiting
Research Team
S
Sarah Sunshine, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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