Actively Recruiting

Age: 18Years - 90Years
All Genders
Healthy Volunteers
NCT06545981

Ocular Perfusion in Patients With Idiopathic Intracranial Hypertension

Led by Medical University of Vienna · Updated on 2024-08-30

48

Participants Needed

1

Research Sites

117 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The proposed study aims to evaluate optic nerve head blood flow and microcirculation in patients with idiopathic intracranial hypertension. For this purpose, optic nerve head blood flow will be examined in patients with IIH before and after therapy and additionally compared with healthy age- and sex-matched control subjects. In addition, other parameters will be measured, in particular retinal blood flow, retinal oxygen saturation and retinal neurovascular coupling.

CONDITIONS

Official Title

Ocular Perfusion in Patients With Idiopathic Intracranial Hypertension

Who Can Participate

Age: 18Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women aged 18 years or older
  • Signed informed consent
  • Newly diagnosed idiopathic intracranial hypertension or relapse of idiopathic intracranial hypertension
  • Non-smokers
  • Men and women aged 18 years or older
  • Signed informed consent
  • Normal eye exam findings unless considered clinically irrelevant by the investigator
  • Normal medical history unless considered clinically irrelevant by the investigator
  • Non-smokers
Not Eligible

You will not qualify if you...

  • Blood donation in the three weeks before the study
  • Symptoms of a clinically relevant illness in the three weeks before the study
  • Eye inflammation or infection within the last 3 months
  • Personal or family history of epilepsy
  • Diabetes mellitus type 1 or type 2
  • History or presence of cerebral vascular diseases like arteriovenous malformation, aneurysm, or major artery problems
  • History or presence of intracranial infections such as meningitis
  • History or presence of other neurological diseases including brain tumor, hydrocephalus, or degenerative diseases
  • Use of corticosteroids or immunosuppressant therapy
  • Pregnant or breastfeeding women
  • Women of childbearing potential not using effective contraception and who are neither menopausal, hysterectomized, nor sterilized

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Medical University of Vienna

Vienna, Austria, 1090

Actively Recruiting

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Research Team

G

Gerhard Garhöfer

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Ocular Perfusion in Patients With Idiopathic Intracranial Hypertension | DecenTrialz