Actively Recruiting

Age: 18Years +
All Genders
NCT04642352

Office-Based Superior Laryngeal Nerve Block for Treatment of Neurogenic Cough

Led by University of Alabama at Birmingham · Updated on 2026-05-08

50

Participants Needed

1

Research Sites

247 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate if office-based injection of a local anesthetic/steroid combination at the area of one superior laryngeal nerve can decrease cough frequency and alleviate symptoms of chronic cough in patients with neurogenic cough.

CONDITIONS

Official Title

Office-Based Superior Laryngeal Nerve Block for Treatment of Neurogenic Cough

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Ability to speak and understand English
  • Ability to provide informed consent
  • Cough lasting 8 weeks or more with suspected nerve-related cause based on history
  • Persistent cough despite treatment of reflux, asthma, and allergic causes as per clinical workup
Not Eligible

You will not qualify if you...

  • Age under 18 years
  • Unable or unwilling to provide informed consent
  • Known cough cause other than nerve irritation (e.g., reflux, asthma, allergic rhinitis, COPD)
  • Starting new neuromodulator medications at injection time
  • Nissen fundoplication surgery within the last year
  • Smoking within the past 5 years
  • Allergy to bupivacaine or Kenalog-40

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Alabama at Birmingham

Birmingham, Alabama, United States, 35233

Actively Recruiting

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Research Team

B

Blake Simpson, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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