Actively Recruiting
OGTT at Home Using CGM vs at the Clinic
Led by Linkoeping University · Updated on 2026-03-24
75
Participants Needed
3
Research Sites
811 weeks
Total Duration
On this page
Sponsors
L
Linkoeping University
Lead Sponsor
R
Region Jönköping County
Collaborating Sponsor
AI-Summary
What this Trial Is About
This randomized, crossover study evaluates the feasibility and accuracy of a self-administered oral glucose tolerance test (OGTT) at home using continuous glucose monitoring (CGM) compared to a standard clinic-based OGTT. Participants with prediabetes will undergo both home-based and clinic-based OGTTs, with glucose levels measured via CGM and venous plasma glucose. The primary outcome is the correlation between CGM-based glucose values and standard OGTT results. Secondary outcomes include diagnostic agreement, metabolic hormone associations, and feasibility of home-based testing as a diagnostic tool for dysglycemia.
CONDITIONS
Official Title
OGTT at Home Using CGM vs at the Clinic
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 70 years
- Prediabetes indicated by at least two of the following measured on separate occasions or by different analyses within the past 2 years:
- Fasting venous plasma glucose between 6.1 and 6.9 mmol/L
- Non-fasting venous plasma glucose between 7.8 and 11.0 mmol/L
- HbA1c between 39 and 47 mmol/mol
- Access to a smartphone compatible with the CGM app and Bluetooth connectivity
- Ability to read and respond to online instructions and questionnaires in Swedish
You will not qualify if you...
- Type 2 diabetes indicated by at least two of the following measured on separate occasions or by different analyses:
- Fasting venous plasma glucose 7.0 mmol/L or higher
- Non-fasting venous plasma glucose 11.1 mmol/L or higher
- HbA1c 48 mmol/mol or higher
- Previous bariatric surgery such as gastric bypass or sleeve surgery
- Body mass index under 20 kg/m2
- Body weight under 43 kg
- Current pregnancy
- Regular use of GLP-1 receptor agonists, SGLT-2 inhibitors, acetaminophen, or ascorbic acid supplements during the study
- Fear of needle sticks
- Working shift hours during the study period
- Involvement in study design, data collection, analysis, or recruitment
AI-Screening
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Trial Site Locations
Total: 3 locations
1
Primary Health Care Center Bra Liv Rosenhälsan
Huskvarna, Jönköping County, Sweden, 55185
Actively Recruiting
2
Primary Health Care Center Cityhälsan Centrum
Norrköping, Norrköping, Sweden, 60239
Actively Recruiting
3
Primary Care Center Vårdcentralen Kärna
Linköping, Östergötland County, Sweden, 58662
Actively Recruiting
Research Team
P
Peder af Geijerstam, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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