Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
NCT05364125

Olfactory Training on Smell Dysfunction Patients in HK

Led by Pamela Youde Nethersole Eastern Hospital · Updated on 2025-06-03

80

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

* Causes of olfactory dysfunction can be classified into conductive and sensorineural causes. * Conductive causes are mainly due to structural nasal problem, which can be treated by nasal surgery * Sensorineural causes included post-infection, post-head injury, post Head and Neck irradiation and other central nervous system diseases. * Olfactory Training is well established treatment for sensorineural olfactory dysfunction in foreign countries. * Olfactory Training by neurological chemosensory stimulation using aromatic substances delivered via electronic portable aromatic rehabilitation (EPAR) diffuser was proved to be effective treatment in COVID-19 related olfactory dysfunction in recent Hong Kong study. * However, there is a lack of local study on the effect of Olfactory Training in other non-COVID-19 sensorineural causes of olfactory dysfunction in Hong Kong population.

CONDITIONS

Official Title

Olfactory Training on Smell Dysfunction Patients in HK

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Olfactory dysfunction lasting more than 6 months and less than 5 years
  • Age between 18 and 70 years
Not Eligible

You will not qualify if you...

  • History of significant head injury (fracture, intracerebral hemorrhage)
  • History of brain surgery
  • History of nasal surgery
  • Active nasal disease
  • Active neurological disease
  • Poor premorbid status or non-communicable patients
  • Mentally incompetent patients
  • Younger than 18 years old
  • Pregnancy
  • Hypersensitivity to the aromatic substances used in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Pamela Youde Nethersole Eastern Hospital

Hong Kong, Hong Kong

Actively Recruiting

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Research Team

K

Kai Chuen Fergus Wong, FRCSEd(ORL)

CONTACT

K

Ka Chung Kwan, FRCSEd(ORL)

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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