Olfactory Training for Treating Persistent Smell Problems After COVID-19 Infection Comparison of Two Different Scent Sets Over 12 Weeks

What this Trial Is About

This research evaluates olfactory training as a treatment for persistent smell loss after COVID-19 infection. The study compares the effects of two different sets of scents on improving olfactory function over a 12-week period. Participants have ongoing problems with smell following COVID-19 and will be assessed using various smell tests and questionnaires to measure changes in smell perception and related symptoms like parosmia and phantosmia. Participants are randomly assigned to one of two groups, each using a different set of four scents. One group will train with rose, orange, clove, and eucalyptus, while the other group will use cheese, coffee, strawberries, and lemon. Training is done twice daily for five minutes per session over 12 weeks. Participants attend an initial meeting for assessments and training instructions, then complete the training at home, followed by a final visit to repeat the tests. During the study, participants undergo several evaluations including smell identification tests UPSIT and Sniffin Sticks, questionnaires on quality of life and olfactory symptoms, and assessments for nasal obstruction and smell distortions. These tests are done at the start and end of the 12-week training. Data about medical history and demographics are also collected to analyze the outcomes. The total study duration for each participant is about 12 weeks of training plus initial and final assessments.

Olfactory Training as a Treatment for Olfactory Dysfunction Post COVID-19