Actively Recruiting
Olfactory Training as a Treatment for Persistent Smell Dysfunction After COVID-19 Infection
Led by Université du Québec à Trois-Rivières · Updated on 2024-12-17
70
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate the effects of olfactory training on persistent smell problems following COVID-19 infection. The study focuses on comparing the outcomes of two different sets of odors used in olfactory training over a 12-week period. Researchers will assess changes in smell function and related symptoms such as parosmia and phantosmia using various smell tests and questionnaires. Participants are randomly assigned to one of two groups: one group will smell four scents (rose, orange, clove, eucalyptus) twice daily for five minutes each session, and the other group will use a different set of four scents (cheese, coffee, strawberries, lemon) with the same schedule. The training lasts for 12 weeks. Initial and final meetings include detailed smell evaluations and questionnaires, with participants receiving instructions and a training kit at the start. During the study, participants will undergo smell tests including the UPSIT and Sniffin' Sticks, and complete questionnaires on the impact of smell dysfunction on quality of life. Researchers will also assess nasal obstruction and record symptoms of parosmia and phantosmia. Measurements are taken before and after the 12-week training. The total involvement includes an initial session, 12 weeks of home training, and a final evaluation session.
CONDITIONS
Brief Title
Olfactory Training As a Treatment for Olfactory Dysfunction Post COVID-19
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient diagnosed positive for COVID-19 with persistent olfactory dysfunction
- Willing and able to provide written informed consent
- Understand and read the French language
- Have an internet connection and a working email address
You will not qualify if you...
- Anosmia and hyposmia before COVID-19
- Known chronic rhinosinusitis with or without nasal polyposis
- Received radiotherapy or chemotherapy for head and neck tumors
- Diagnosis of Alzheimer's, Parkinson's, multiple sclerosis or other neurodegenerative disease
- Brain tumor or ENT diagnosis
- History of naso-sinus surgery
- History of traumatic brain injury
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 weeks
Participants undergo olfactory training by smelling four different odors twice daily for five minutes per session over 12 weeks.
1 initial meeting and 1 final meeting (both in-person)
Trial Site Locations
Total: 1 location
1
Université du Québec à Trois-Rivières
Trois-Rivières, Quebec, Canada, G8Z 4M3
Actively Recruiting
Research Team
J
Johannes A Frasnelli, PhD
F
Frank Cloutier, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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