Actively Recruiting

Phase 1
Age: 18Years +
All Genders
Healthy Volunteers
NCT05683184

OMAR Opioid Use Disorder

Led by Yale University · Updated on 2026-04-28

30

Participants Needed

1

Research Sites

196 weeks

Total Duration

On this page

Sponsors

Y

Yale University

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this research study is to examine the endocannabinoid (eCB) function in vivo in individuals with opioid use disorder (OUD) by measuring cannabinoid receptor 1 (CB1R) availability.

CONDITIONS

Official Title

OMAR Opioid Use Disorder

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Able to provide informed consent
  • Male and female 18 years and older
  • DSM-5 diagnosis of opioid use disorder (for OUD group)
  • Physically healthy with no clinically unstable medical conditions
  • Written informed consent and ability to comply with study procedures
Not Eligible

You will not qualify if you...

  • Current neuro-psychiatric illness or severe systemic disease (except opioid use disorder in OUD group)
  • Presence of ferromagnetic metal in the body or a heart pacemaker
  • Prior exposure to ionizing radiation exceeding recommended limits when combined with study tracer
  • Claustrophobia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Connecticut Mental Health Center, Clinical Neuroscience Research Unit

New Haven, Connecticut, United States, 06519

Actively Recruiting

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Research Team

A

Anahita Bassir Nia, MD

CONTACT

A

Angelina Contreras

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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