Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
NCT05297279

OMEGA - Dietary Intervention - COPD Trial

Led by Johns Hopkins University · Updated on 2026-03-16

200

Participants Needed

1

Research Sites

287 weeks

Total Duration

On this page

Sponsors

J

Johns Hopkins University

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

A randomized controlled trial of a food delivery dietary intervention targeting increased omega-3 intake to determine whether dietary modifications can improve Chronic Obstructive Pulmonary Disease (COPD) outcomes and attenuate the adverse effects of particulate matter on respiratory health. Investigators believe that study results will comprehensively address the impact of an evidence-based nutrition intervention on COPD health and provide a framework for dietary intervention within other chronic diseases disproportionately impacting susceptible, low-income populations.

CONDITIONS

Official Title

OMEGA - Dietary Intervention - COPD Trial

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 40 years or older
  • Physician diagnosis of COPD
  • Global Initiative for Obstructive Lung Disease (GOLD) Stage II-IV with FEV1/FVC <70% and FEV1 <80%, or if FEV1/FVC <70% and FEV1 ≥80%, CAT score ≥10
  • Tobacco exposure of 10 or more pack-years
  • Meets poverty criteria by living in a neighborhood with at least 10% poverty, or no private health insurance, or education level of high school or less
  • Low omega-3 intake (daily EPA+DHA less than 500 mg) at screening
  • Willingness to follow dietary recommendations
Not Eligible

You will not qualify if you...

  • Planning to change residence during the study
  • Having other chronic lung diseases except asthma not considered primary diagnosis
  • Pregnancy or breastfeeding
  • Unwillingness to eat seafood

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Johns Hopkins Bayview Campus

Baltimore, Maryland, United States, 21224

Actively Recruiting

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Research Team

W

Wendy Lorizio, MD, MPH

CONTACT

M

Maggie Maly

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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OMEGA - Dietary Intervention - COPD Trial | DecenTrialz