Actively Recruiting

Phase Not Applicable
Age: 18Years - 40Years
All Genders
Healthy Volunteers
NCT05822141

Omega-3 Fatty Acids as Regulators of Brown Adipose Tissue During Cold Exposure

Led by Indiana University · Updated on 2025-04-07

30

Participants Needed

1

Research Sites

129 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This clinical trial will assess the whether fish oil supplementation can modulate brown fat activation, shivering, thermal comfort and skin blood flow during cold exposure.

CONDITIONS

Official Title

Omega-3 Fatty Acids as Regulators of Brown Adipose Tissue During Cold Exposure

Who Can Participate

Age: 18Years - 40Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female, between the ages of 18 to 40 years.
  • Body Mass Index (BMI) of 18.5 to 24.9 kg/m2
  • Considered "moderately to highly active" by the International Physical Activity Questionnaire (IPAQ) and the Physical Activity Readiness Questionnaire (PAR-Q+)
Not Eligible

You will not qualify if you...

  • History of smoking or recreational smoking, hyperlipidemia, hypertension/cardiovascular disease, diabetes, renal disease, neurological disease, metabolic disease, and bleeding disorders or delayed clotting time.
  • Taking SSRI's (antidepressants and anxiety medication), ADD/ADHD medication, and chronically consume pain medication (Aleve, Tylenol, CBD, etc).
  • Have or have had chronic disorders of the rectum (e.g., cancer, surgery, active hemorrhoids, etc.) or who currently have related acute conditions (diarrhea, constipation, etc.).
  • Have or have had a diagnosis of disorders related to immune suppression and/or autoimmune disease.
  • Are pregnant or planning on being pregnant.
  • Resting blood pressure of > 130mmHg systolic or 90 mmHg diastolic.
  • Resting Pulse rate of > 100 bpm.
  • History of regularly consuming fish oil supplements and/or regularly eating more than one fish meal per week.
  • Consuming more than one fish meal per week during the study.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Human Perfromance Lab, Indiana University

Bloomington, Indiana, United States, 47405

Actively Recruiting

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Research Team

T

Timothy D Mickleborough, PhD

CONTACT

A

Abigail S Sogard, B.S.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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