Actively Recruiting
Once Weekly Infant Corticosteroid Trial for DMD
Led by Anne M. Connolly · Updated on 2025-08-13
26
Participants Needed
4
Research Sites
291 weeks
Total Duration
On this page
Sponsors
A
Anne M. Connolly
Lead Sponsor
C
Children's Hospital Medical Center, Cincinnati
Collaborating Sponsor
AI-Summary
What this Trial Is About
The hypothesis tested here is that a lower dose of intermittent oral corticosteroids (5mg/kg/week) will be equally effective to the 10mg/kg/week dose.
CONDITIONS
Official Title
Once Weekly Infant Corticosteroid Trial for DMD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects ages 1 month through 30 months
- Weakness consistent with Duchenne muscular dystrophy on exam
- Creatine kinase level at least 20 times the upper limit of normal
- Genetic mutation known to cause Duchenne muscular dystrophy
You will not qualify if you...
- Prior treatment with glucocorticosteroids
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Lurie Children's Hospital of Chicago
Chicago, Illinois, United States, 60611
Actively Recruiting
2
University of Cincinnati
Cincinnati, Ohio, United States, 45220
Actively Recruiting
3
Nationwide Children's Hospital
Columbus, Ohio, United States, 43205
Actively Recruiting
4
University of Texas Southwestern
Dallas, Texas, United States, 75235
Actively Recruiting
Research Team
S
Sara Marshall
CONTACT
K
Kevin Warf
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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