Actively Recruiting
Oncolytic Adenovirus(H101) Combined With PD-1 Inhibitors in Patients With Advanced Malignant Pleural Mesothelioma
Led by Tianjin Medical University Second Hospital · Updated on 2023-09-11
15
Participants Needed
1
Research Sites
158 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate the efficacy and safety of Oncolytic Adenovirus(H101) combined with PD-1 inhibitor in patients with advanced malignant pleural mesothelioma who have previously been resistant to advanced PD-1 inhibitors.
CONDITIONS
Official Title
Oncolytic Adenovirus(H101) Combined With PD-1 Inhibitors in Patients With Advanced Malignant Pleural Mesothelioma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-75 years old (including boundaries), any gender
- Confirmed late stage malignant pleural mesothelioma patients who have failed immunotherapy
- Ability to understand and sign informed consent form by patient or legal representative
- At least one lesion suitable for safe intratumoral or intrapleural injection, with diameter ≥ 1cm by spiral CT or ≥ 2cm by ordinary CT, measurable by imaging
- ECOG performance status score between 0 and 2
You will not qualify if you...
- Physician believes patient cannot provide continuous follow-up information
- Presence of any uncontrollable clinical problems such as severe mental, neurological, cardiovascular, respiratory, or other systemic diseases
- Contraindications to oncolytic adenoviruses, PD-1 inhibitors, or related drugs
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Tianjin Medical Unversity Second Hospital
Tianjin, Tianjin Municipality, China
Actively Recruiting
Research Team
H
Haitao Wang, Ph.D
CONTACT
J
Jinhuan Wang, Ph.D
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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