Comparing Ondansetron Lozenge and Intravenous to Prevent Shivering in Children Having Tonsillectomy

What this Trial Is About

This trial investigates the prevention of shivering in children aged 4 to 15 years undergoing tonsillectomy, a common surgery in this age group. Shivering is a spontaneous muscle activity that can increase metabolism and cause discomfort after surgery. The study compares two methods of administering ondansetron, a drug known to block certain receptors and used to prevent shivering during and after operations. Participants will be randomly assigned to one of three groups one group will receive a 4 mg ondansetron lozenge two hours before surgery, another group will receive a 4 mg intravenous dose just before surgery, and a control group will not receive ondansetron. The study aims to evaluate the effect of these different administration routes on shivering prevention. During the study, researchers will monitor the incidence of shivering within 24 hours after surgery, as well as other outcomes like postoperative nausea and vomiting, body temperature during surgery, and any adverse effects. The trial will follow participants through the surgery and the first 24 hours postoperatively to assess these outcomes and safety.

Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Tonsillectomy