One-Stop manaGemEnT For A Swift Initiation of Endovascular Therapy - An International, Multicenter, Pragmatic Randomized Controlled Trial (GET-FAST

What this Trial Is About

Stroke caused by a blocked blood vessel in the brain, known as acute ischemic stroke (AIS), is a major cause of death and long-term disability. The trial evaluates a new "One-Stop management" approach for delivering endovascular therapy (EVT), where both brain imaging and treatment are done in the same room to reduce delays. This approach is compared to the standard two-room process to see if it improves patient outcomes, especially disability and daily function 90 days after treatment. The trial has two groups: one group receives One-Stop management where patients are taken directly to the angiography room for brain imaging using flat panel CT and angiography, followed immediately by EVT if needed. The other group follows usual care with initial imaging in a multidetector CT room before EVT if a treatable vessel blockage is found. Randomization assigns patients to either approach but all receive care following current medical guidelines. The study includes all patients regardless of stroke type to measure overall impact. Participants will be assessed for disability and dependency in daily activities at 90 days after treatment, with additional evaluations of neurological improvement, cognitive function, and quality of life up to one year. The trial uses existing hospital imaging systems and tracks long-term outcomes to determine if One-Stop management leads to faster treatment and better recovery. Patients are monitored closely throughout, and the study aims to improve stroke care and reduce healthcare costs by enabling more patients to regain independence.

One-Stop manaGemEnT For A Swift Initiation of Endovascular Therapy