Actively Recruiting
One-year Patency Comparison Between Radial Artery and No-touch Saphenous Vein Grafts in Women Undergoing Isolated CABG
Led by University of Sao Paulo General Hospital · Updated on 2025-12-12
150
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
Sponsors
U
University of Sao Paulo General Hospital
Lead Sponsor
I
Instituto Nacional de Cardiologia
Collaborating Sponsor
AI-Summary
What this Trial Is About
The use of a graft from the left internal thoracic artery to the left anterior descending artery has become the gold standard for the indication of coronary artery bypass grafting. However, choosing a graft for the second-best coronary artery, focusing on long-term patency, is still a challenge. The saphenous vein using the "no-touch" technique is an alternative to a radial artery graft, but there is little evidence, especially in women. This randomized clinical study aims to compare the patency of these grafts in the second-best coronary artery in women undergoing coronary artery bypass grafting.
CONDITIONS
Official Title
One-year Patency Comparison Between Radial Artery and No-touch Saphenous Vein Grafts in Women Undergoing Isolated CABG
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women aged 18 years or older and younger than 75 years
- Undergoing isolated and primary myocardial revascularization surgery
- Diagnosed with triarterial coronary artery disease involving vessels subject to surgical revascularization
- Left ventricular ejection fraction greater than 35%
- Target coronary vessels in the left circumflex artery and right coronary artery territories
- Target vessels at least 1.5 mm in diameter with proximal obstructive lesions of at least 70%
You will not qualify if you...
- Lack of written informed consent
- Poorly controlled diabetes with glycated hemoglobin >8 mg/dl
- Emergency or salvage surgery due to critical clinical condition
- Renal failure with glomerular filtration rate <30 mL/min
- Inability to use saphenous or radial vein due to positive Allen test or abnormal Doppler flow
- History of vasculitis, Raynaud's syndrome, varicose veins, or previous saphenous vein removal
- Advanced peripheral arterial disease
- Known allergy to contrast agents used in radiological procedures
- Geographic inaccessibility preventing follow-up
- Lack of adherence to medical guidelines or prescribed medications
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina de São Paulo
São Paulo, São Paulo, Brazil, 05403-900
Actively Recruiting
Research Team
O
Omar A V Mejia, MD, PhD
CONTACT
L
Leonardo L Lacava, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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