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Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
FEMALE
ID06179329

Comparing Radial Artery and No-Touch Saphenous Vein Grafts in Women Undergoing Coronary Artery Bypass Surgery A Randomized Study on Graft Patency and Outcomes

Led by University of Sao Paulo General Hospital · Updated on 2025-12-12

150

Participants Needed

1

Research Sites

156 weeks

Total Duration

AI-Summary

What this Trial Is About

Researchers are comparing two types of grafts used in coronary artery bypass grafting CABG for women with heart disease involving three major arteries. The study aims to evaluate which graftthe radial artery or a no-touch saphenous vein graftshows better long-term openness patency when used in the second most important coronary artery. This trial focuses specifically on women and addresses a current challenge in choosing the best graft for improving surgical outcomes. Participants will be randomly assigned to one of two groups one group will receive a radial artery graft for the anterolateral wall and a no-touch saphenous vein graft for the right coronary artery area, while the other group will have the reverse arrangement. The randomization is done just before surgery to determine which grafting strategy will be used. This controlled procedure is designed to compare outcomes in a structured and unbiased way. Women aged 18 to 75 undergoing their first isolated CABG with specific heart artery conditions will be involved. Follow-up includes an angiography exam one year after surgery to assess graft patency, and clinical outcomes will also be evaluated 30 days after surgery. Safety and adherence are closely monitored. The total participation includes preoperative assessment, surgery, and scheduled follow-ups to track the success and any complications associated with the grafts.

CONDITIONS

Brief Title

One-year Patency Comparison Between Radial Artery and No-touch Saphenous Vein Grafts in Women Undergoing Isolated CABG

Research Team

O

Omar A V Mejia, MD, PhD

L

Leonardo L Lacava, MD

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