Actively Recruiting
Online Adaptive Radiotherapy for Cervical Cancer
Led by Peking Union Medical College Hospital · Updated on 2026-01-08
124
Participants Needed
1
Research Sites
221 weeks
Total Duration
On this page
Sponsors
P
Peking Union Medical College Hospital
Lead Sponsor
A
Affiliated Hospital of Jiangsu University
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to evaluate the clinical efficacy and safety of online adaptive radiotherapy for cervical cancer patients received radical radiotherapy. By comparing with image-guided radiotherapy, the study explores the potential advantages of online adaptive radiotherapy in reducing treatment toxicity and improving local control.
CONDITIONS
Official Title
Online Adaptive Radiotherapy for Cervical Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 to 80 years old
- Diagnosed with cervical squamous carcinoma confirmed by pathology
- 2018 FIGO Stage Ib3, II, IIIB, or IIIC1 cervical cancer
- Planned radical pelvic radiotherapy plus concurrent platinum-based chemotherapy (cisplatin 30-40mg/m2 or carboplatin), starting within first week for at least 5 courses
- ECOG performance status 0 to 2
- Life expectancy over 6 months
- Able to lie down for more than 30 minutes
- Fully voluntary and able to cooperate, with signed informed consent
- Complete blood count and metabolic tests within 14 days before enrollment meeting NEUT ≥ 1.5*10^9/L, HGB ≥ 60g/L, platelets ≥ 100x10^9/L, creatinine <1.5 mg/dL, AST and ALT within twice upper limit of normal
- Completed all baseline assessments before treatment
- Eligible for regular follow-up
You will not qualify if you...
- Previous radiotherapy or chemotherapy
- Previous radical surgery for cervical cancer
- History of other malignant tumors
- Pregnant or breastfeeding
- Severe uncontrolled cardiovascular, urinary, digestive, respiratory, hematological, or central nervous system diseases
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Peking union medical college hospital
Beijing, China, 100730
Actively Recruiting
Research Team
S
Shuai Sun
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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