Actively Recruiting

Phase Not Applicable
Age: 22Years +
All Genders
NCT06742801

Onyx™ Liquid Embolic IDE Clinical Study

Led by Medtronic Endovascular · Updated on 2026-05-01

119

Participants Needed

16

Research Sites

103 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate the safety and effectiveness of Onyx™ LES in the treatment of subjects with active arterial bleeding in the peripheral vasculature outside of the heart and brain.

CONDITIONS

Official Title

Onyx™ Liquid Embolic IDE Clinical Study

Who Can Participate

Age: 22Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient is 63; 22 years old.
  • Active arterial bleeding in peripheral vasculature confirmed by radiologic and/or endoscopic imaging and suitable for embolization treatment.
  • Patient or legally authorized representative can provide written consent.
  • Life expectancy greater than 30 days as judged by investigator.
  • Target treatment area has not received prior embolization treatment.
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding.
  • Symptoms of active infection.
  • Currently participating in another investigational study involving drug, biologic, or device.
  • Allergy or contraindication to contrast agents used in angiography, CT, or catheterization.
  • Known allergy to components of Onyx14.
  • Target vasculature judged unsuitable for Onyx14 delivery.
  • More than 4 target lesions require embolization according to investigator's assessment.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 16 locations

1

Mayo Clinic

Phoenix, Arizona, United States, 85054

Actively Recruiting

2

University of California, Irvine

Irvine, California, United States, 92627

Actively Recruiting

3

Stanford Medical Center

Palo Alto, California, United States, 94304

Actively Recruiting

4

UCHealth University of Colorado Hospital

Aurora, Colorado, United States, 80045

Actively Recruiting

5

Yale New Haven

New Haven, Connecticut, United States, 06510

Actively Recruiting

6

University of Chicago

Chicago, Illinois, United States, 60637

Actively Recruiting

7

University of Iowa Hospitals and Clinics

Iowa City, Iowa, United States, 52242

Actively Recruiting

8

Masschusetts General Hospital

Boston, Massachusetts, United States, 02114

Actively Recruiting

9

CHI Health Creighton University Medical Center-Bergan-Mercy

Omaha, Nebraska, United States, 68124

Actively Recruiting

10

Albany Medical Center

Albany, New York, United States, 12208

Actively Recruiting

11

The Mount Sinai

New York, New York, United States, 10029

Actively Recruiting

12

University Hospitals Cleveland Medical Center

Cleveland, Ohio, United States, 44106

Actively Recruiting

13

The Ohio State University

Columbus, Ohio, United States, 43210

Actively Recruiting

14

Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37212

Actively Recruiting

15

Univ Of Texas Southwestern

Dallas, Texas, United States, 75235

Actively Recruiting

16

The University of Texas Health Science Center at Houston

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

J

Janki Shah

CONTACT

L

Liza Marie

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Onyx™ Liquid Embolic IDE Clinical Study | DecenTrialz