Actively Recruiting
Open-label Placebo for Pain Management in Adolescents and Young Adults Undergoing Bernese Periacetabular Osteotomy
Led by University of California, San Francisco · Updated on 2026-04-29
64
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this randomized controlled trial, 64 participants undergoing PAO at UCSF will be enrolled and randomized to receive either COLP plus treatment as usual (TAU) or TAU alone. Patients in the COLP arm will receive placebo pills alongside prescribed opioids and at scheduled intervals, beginning on postoperative day one. Weekly follow-up will be conducted for six weeks postoperatively via remote surveys and video visits.
CONDITIONS
Official Title
Open-label Placebo for Pain Management in Adolescents and Young Adults Undergoing Bernese Periacetabular Osteotomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 13 to 40 years old
- Undergo primary Bernese Periacetabular osteotomy (PAO) for symptomatic developmental dysplasia of the hip (DDH)
- Opioid-nafve prior to operation
- Capable of completing study procedures, including daily pain and medication diaries and weekly questionnaires
You will not qualify if you...
- Undergoing PAO revision or any concurrent major surgical procedure
- History of opioid use, substance use disorders, or alcohol abuse
- Cognitive or physical impairments interfering with consent or study tasks
- Pregnant individuals or those planning pregnancy during the study period
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California San Francisco
San Francisco, California, United States, 94158
Actively Recruiting
Research Team
T
Tripta Rughwani
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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