Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
NCT06542991

An Open-label Study on the Clinical Efficacy of rTMS Intervention in PD

Led by Anhui Medical University · Updated on 2024-08-07

20

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To demonstrate that intervention targeting the supplementary motor area (SMA) using precise navigation positioning can effectively improve motor symptoms in patients with Parkinson's disease.

CONDITIONS

Official Title

An Open-label Study on the Clinical Efficacy of rTMS Intervention in PD

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 40 years or older
  • Diagnosis meeting Movement Disorder Society standards
  • No drug adjustment within 4 weeks before and during treatment
  • Movement Disorder Society Unified Parkinson's Disease Rating Scale Part III score of 8 or higher
  • Hoehn-Yahr rating between 1 and 4
  • Mini-Mental State Examination score of 24 or higher
  • Ability to cooperate with behavioral tests and transcranial magnetic stimulation therapy
Not Eligible

You will not qualify if you...

  • Evidence of focal brain injury or severe leukoencephalopathy on MRI/CT
  • Secondary parkinsonism syndromes such as vascular or drug-induced parkinsonism
  • Severe head trauma, prior brain surgery, or deep brain stimulation treatment
  • Presence of ferromagnetic implants like cochlear implants or cardiac pacemakers
  • Personal or first-degree family history of epilepsy or unexplained loss of consciousness, or current use of anticonvulsant drugs
  • Diagnosis of neuropsychiatric disorders other than Parkinson's disease
  • History of drug abuse
  • Participation in any clinical trial within the past 6 months
  • Pregnant or breastfeeding women, or individuals planning to conceive within 6 months
  • Any other condition deemed unsuitable by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cognitive Neuropsychology Lab Anhui Medical University

Hefei, Anhui, China

Actively Recruiting

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Research Team

K

Kai Wang, Ph.D.

CONTACT

P

Panpan Hu, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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An Open-label Study on the Clinical Efficacy of rTMS Intervention in PD | DecenTrialz