Actively Recruiting

Phase 4
Age: 12Years +
All Genders
NCT06484868

Open-label Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy

Led by Amryt Pharma · Updated on 2025-07-03

12

Participants Needed

12

Research Sites

207 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is an Open Label, Phase IV, Post Authorisation Study to Evaluate the Efficacy, Safety and Immunogenicity of Daily Subcutaneous Metreleptin Treatment in people with Partial Lipodystrophy

CONDITIONS

Official Title

Open-label Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy

Who Can Participate

Age: 12Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis of familial or acquired partial lipodystrophy
Not Eligible

You will not qualify if you...

  • Treatment with any Investigational Medicinal Product within 6 months or 5 times the terminal half-life of the corresponding IMP, whichever is longer, before the screening visit.
  • Other protocol defined inclusion/exclusion criteria apply

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 12 locations

1

Centre Hospitalier Régional Universitaire de Lille (CHRU) - Hôpital Claude Huriez

Lille, France

Actively Recruiting

2

Hopital Pitie-Salpetriere

Paris, France

Actively Recruiting

3

Hôpital Saint-Antoine

Paris, France

Actively Recruiting

4

Centre Hospitalier Lyon-Sud

Pierre-Bénite, France

Actively Recruiting

5

Charite-Universitaetsmedizin Berlin - Campus Charite Mitte (CCM)

Berlin, Germany

Actively Recruiting

6

Universitaetsklinikum Ulm - Klinik fuer Kinder- und Jugendmedizin

Ulm, Germany

Not Yet Recruiting

7

Azienda Ospedaliero-Universitaria di Bologna Policlinico S. Orsola-Malpighi

Bologna, Italy

Actively Recruiting

8

Universitá degli Studi "Magna Graecia" di Catanzaro

Catanzaro, Italy

Not Yet Recruiting

9

Azienda Ospedaliero Universitaria Maggiore della Carità di Novara

Novara, Italy

Actively Recruiting

10

Azienda Ospedaliero Universitaria Pisana - Stabilimento di Cisanello

Pisa, Italy

Actively Recruiting

11

A.S.U Integrata di Udine - Presidio Ospedaliero Santa Maria della Misericordia

Udine, Italy

Actively Recruiting

12

Cambridge University Hospitals NHS Foundation Trust - Addenbrookes Hospital

Cambridge, United Kingdom

Not Yet Recruiting

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Research Team

J

Janet Boylan

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Open-label Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy | DecenTrialz