Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT05929911

Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD

Led by Montefiore Medical Center · Updated on 2025-06-08

20

Participants Needed

1

Research Sites

100 weeks

Total Duration

On this page

Sponsors

M

Montefiore Medical Center

Lead Sponsor

N

National Institute of Allergy and Infectious Diseases (NIAID)

Collaborating Sponsor

AI-Summary

What this Trial Is About

People living with HIV (PLWH) have a higher rate of post-traumatic stress disorder (PTSD) diagnosis than the general population. Comorbid PTSD is also associated with negative HIV-related health outcomes. Unfortunately, little outcome research has examined the usefulness of PTSD treatments for PTSD. This pilot study adapts for PLWH a non-exposure based psychotherapy for PTSD focused on reflecting on one's emotions and relationships and understanding and working through how trauma may have disrupted them. The study team is interested in better understanding the needs of PLWH with PTSD, learning whether PLWH with PTSD find this treatment acceptable and helpful, and beginning to understand the relationship between HIV-related health factors (e.g., inflammation and stress biology) and PTSD, and how these health factors may improve during treatment.

CONDITIONS

Official Title

Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of PTSD based on DSM-5 with a severity score of 25 or higher on the Clinician Administered PTSD Scale
  • Confirmed HIV diagnosis by medical records or testing
  • Stable psychiatric or psychotropic medication use for at least 2 months and ongoing during treatment
Not Eligible

You will not qualify if you...

  • Diagnosis of psychosis
  • Diagnosis of bipolar I disorder
  • Acute suicidality
  • Current substance use disorder
  • Organic mental syndrome or intellectual disability
  • Unstable medical conditions not related to HIV

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Albert Einstein College of Medicine

The Bronx, New York, United States, 10461

Actively Recruiting

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Research Team

J

John R Keefe, PhD

CONTACT

B

Barbara L Milrod, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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