Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05571033

Operant Conditioning of the Soleus Stretch Reflex in Adults With Cerebral Palsy

Led by Burke Medical Research Institute · Updated on 2023-09-26

12

Participants Needed

1

Research Sites

221 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

12 adults with spastic CP will complete 6 baseline sessions and 24 down conditioning sessions held 3 times/week. All clinical and physiological assessments collected at baseline will be reassessed after study completion, and follow ups after 2 weeks, 1 month and 3 months. The soleus H reflex (electric analogue of the stretch reflex) will be elicited in all sessions. In each session, participants will complete 20 baseline trials and 225 down conditioning trials to decrease the magnitude of the H-Reflex.

CONDITIONS

Official Title

Operant Conditioning of the Soleus Stretch Reflex in Adults With Cerebral Palsy

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 and above
  • Diagnosis of spastic Cerebral Palsy
  • Gross Motor Function Classification System level I-III
  • Stable medical background
  • Current medication will remain unchanged for 3 months
  • Provides informed consent
  • Can walk at least 10 meters with or without assistive device
  • Meets minimum study procedure requirements (elicitation of H-reflex)
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Uncontrolled diabetes
  • Weak dorsiflexion
  • History of cardiac conditions
  • Cognitive deficits that interfere with study procedure and steps for completion
  • Botox within 2 months of the study
  • History of ankle surgeries in affected leg (Dorsal root rhizotomy etc.)
  • Regular use of electrical stimulation to lower extremity muscles
  • Cochlear or metal implantations on body
  • No history of seizure after age 2 years
  • Current use of antiseizure medicines
  • Any metal or magnetic components in the head (surgical clips, metal work etc.)
  • Implanted device or cardiac pacemakers (applicable for DS8R too)
  • Skin disorders
  • Damaged skin (wounds, broken skin, or recent scar tissue)
  • Allergy to latex (tape)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Burke Neurological Institute

White Plains, New York, United States, 10605

Actively Recruiting

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Research Team

D

Devina Kumar, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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