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ID06755190

Ophthalmic Multimodal AI-Assisted Medical Decision-Making Using Imaging and Electronic Medical Records

Led by The Eye Hospital of Wenzhou Medical University · Updated on 2025-04-17

5000000

Participants Needed

5

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Visual impairments greatly impact quality of life, making early screening, diagnosis, and treatment of eye diseases essential. This research evaluates an AI-assisted medical decision support system that combines various types of patient data, including images and electronic health records, to improve diagnosis and treatment planning for ocular diseases. The study aims to enhance diagnostic accuracy, streamline clinical workflows, and offer personalized treatment options to improve patient outcomes. The study uses an AI system that integrates multimodal data such as fundus photos, OCT scans, and clinical records. This AI model employs deep learning to provide real-time, personalized diagnostic and prognostic support, predicting disease progression and treatment results. The evaluation involves patients both with and without ocular diseases from multiple medical centers, using retrospective data collected from their electronic health records. Participants have previously received treatment at several hospitals, and their records include ophthalmic images, medical notes, and examination results. Researchers will analyze these data to assess the AI system's diagnostic accuracy, sensitivity, specificity, and decision-making effectiveness over one year. They will also monitor system usability, user satisfaction, treatment adherence, and physician acceptance, aiming to improve clinical decision-making and patient care through this technology.

CONDITIONS

Brief Title

Ophthalmic Multimodal AI-Assisted Medical Decision-Making

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who have received treatment at participating centers including The Eye Hospital of Wenzhou Medical University, First and Second Affiliated Hospitals of Wenzhou Medical University, Zhuhai People's Hospital, and Macau University of Science and Technology Hospital
  • Availability of comprehensive electronic health records including ophthalmic images such as fundus photography, OCT, or slit-lamp images
  • Availability of electronic medical records including diagnosis, treatment, and follow-up notes
  • Availability of examination results such as visual acuity, intraocular pressure, or laboratory tests
  • Patients with a clear and confirmed diagnosis of one or more ocular diseases
  • Patients with sufficient follow-up records to allow assessment of disease progression or prognosis if applicable
Not Eligible

You will not qualify if you...

  • Incomplete or missing critical components of electronic health records
  • Ambiguous or unverified diagnoses that cannot be clearly categorized
  • Duplicate or redundant data from the same patient

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 year

Participants undergo assessment using an AI-based diagnostic and prognostic model that integrates imaging and clinical records to support ophthalmic disease diagnosis and treatment planning.

Visits as needed for imaging and clinical data collection over 1 year

Long-term Monitoring

Duration - Up to 1 year

Participants are observed over time to assess disease progression and treatment outcomes using the AI-assisted system.

Periodic visits according to clinical follow-up schedules

Trial Site Locations

Total: 5 locations

1

ZhuHai Hospital, zhuhai, guangdong

Zhuhai, Guangdong, China

Actively Recruiting

2

First Affiliated Hospital of Wenzhou Medical University

Wenzhou, Zhejiang, China

Actively Recruiting

3

Second Affiliated Hospital of Wenzhou Medical Universit

Wenzhou, Zhejiang, China

Actively Recruiting

4

The Eye Hospital of Wenzhou Medical University

Wenzhou, Zhejiang, China

Actively Recruiting

5

Macau University of Science and Technology Hospital

Macao, Macau, Macau

Actively Recruiting

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Research Team

L

Lan Wang, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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