Actively Recruiting
Opioid-free Anesthesia Protocol for Neurosurgical Supratentorial Tumor Resection
Led by Beijing Tiantan Hospital · Updated on 2025-03-11
170
Participants Needed
1
Research Sites
75 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Opioids have many side effects, such as constipation, urinary retention, itchy skin, respiratory depression, and postoperative nausea and vomiting. These side effects can lead to delayed recovery, longer hospital stays, and increased health care costs. Opioid-free anesthesia is the combination of anti-nociceptive drugs to block the different pathways involved in the transmission of nociceptive information, control pain, avoid opioid-related adverse reactions, and promote patient recovery. At present, opioid-free anesthesia is not widely used in craniocerebral surgery in neurosurgery, and the relevant clinical data are extensive. Therefore, the investigators urgently need to conduct a randomized controlled study to provide clinical evidence for the efficacy and safety of opioid-free anesthesia in neurosurgical patients.
CONDITIONS
Official Title
Opioid-free Anesthesia Protocol for Neurosurgical Supratentorial Tumor Resection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled for craniotomy for supratentorial tumors with general anesthesia
- Aged 18 to 65 years
- American Society of Anesthesiologists (ASA) physical status I to III
- Signed informed consent
You will not qualify if you...
- Body mass index (BMI) 35 kg/m2 or higher
- Severe liver or kidney failure
- Cognitive dysfunction, aphasia, or inability to cooperate with assessments
- Head MRI showing midline brain shift greater than 5 mm
- Undergoing electrophysiological monitoring during surgery
- Pregnant or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beijing Tiantan Hospital
Beijing, China
Actively Recruiting
Research Team
H
Han
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here