Actively Recruiting
Opioid-Free Orthopaedics
Led by Emory University · Updated on 2026-04-30
80
Participants Needed
3
Research Sites
416 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this investigation is to compare effectiveness of this multimodal regimen at controlling postoperative pain with and without the use of opioid medications.
CONDITIONS
Official Title
Opioid-Free Orthopaedics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with advanced arthritis undergoing total joint replacement (shoulder, anatomic, or reverse) in the primary setting
- Patients undergoing orthopedic surgery on finger, hand, wrist, forearm, or elbow
- Patients undergoing orthopedic surgery on hip, knee, ankle, or foot
- Patients who have tried 3 or more months of nonoperative treatment including activity modifications, corticosteroid injections, and physical therapy
- Patients aged 18 years or older who are willing and mentally capable to consent to participate in the study
You will not qualify if you...
- Patients with significant injuries to other bones or organs
- Patients with local infections
- History of alcohol or medical abuse
- Preoperative opioid use within 3 months of surgery
- Advanced kidney or liver disease
- Contraindication to receiving a nerve block
- Uncontrolled diabetes mellitus with HbA1C greater than 9.0
- Prior gastric ulcer that prevents use of Aspirin and anti-inflammatory medications
- Patients with abnormal kidney and liver function tests prior to inclusion
- Patients with Workman's compensation status
- Minors and vulnerable subjects
- Pregnant women
- Patients unwilling to consent to participate
- Patients considered by the investigator to be non-compliant with study schedules or procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
The Emory Clinic
Atlanta, Georgia, United States, 30024
Actively Recruiting
2
Emory University Hospital
Atlanta, Georgia, United States, 30322
Actively Recruiting
3
Emory Orthopedic and Spine Hospital
Tucker, Georgia, United States, 30084
Actively Recruiting
Research Team
A
Alexander Dawes
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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