Actively Recruiting

Phase Not Applicable
Age: 3Years - 17Years
All Genders
NCT06326983

Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery

Led by Boston Children's Hospital · Updated on 2026-01-07

58

Participants Needed

1

Research Sites

98 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham. The overall aim is to evaluate the efficacy of an opioid anesthetic plan (morphine, ketorolac, and acetaminophen versus an opioid sparing anesthetic plan (dexmedetomidine, ketorolac and acetaminophen) for perioperative analgesia and recovery time in patients undergoing tonsillectomies and tonsillotomies at Boston Children's Hospital Waltham. Secondary measures include rescue opioids administered in post-anesthesia care unit (PACU), re-operation secondary to bleeding, emergence delirium, post-operative nausea and vomiting, intraoperative hemodynamics, intraoperative vasopressor administration, and length of procedure.

CONDITIONS

Official Title

Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery

Who Can Participate

Age: 3Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • American Society of Anesthesia classification status I-III
  • Ages 3 years to 17 years
  • Scheduled for tonsillectomy or tonsillotomy with or without adenoidectomy at Boston Children's Hospital Waltham
Not Eligible

You will not qualify if you...

  • Patients not scheduled for primary tonsillectomy or tonsillotomy
  • Patients with known coagulopathies
  • Patients with previous chronic pain syndromes
  • Patients with any condition or allergy preventing randomization to study medications

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Boston Children's Hospital

Waltham, Massachusetts, United States, 02453

Actively Recruiting

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Research Team

J

Jocelyn Booth, BSN

CONTACT

S

Samuel Kim, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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