Actively Recruiting

Phase 2
Phase 3
Age: 18Years +
All Genders
NCT05766891

Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery

Led by M.D. Anderson Cancer Center · Updated on 2026-03-16

225

Participants Needed

1

Research Sites

272 weeks

Total Duration

On this page

Sponsors

M

M.D. Anderson Cancer Center

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

To hypnosedation alone given before and during surgery on reducing opioid use after surgery compared to standard general anesthesia given alone or with hypnosedation.

CONDITIONS

Official Title

Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women
  • Age 18 or older
  • Scheduled for a unilateral breast surgical procedure, with or without sentinel lymph node dissection
  • Able to read, write, and speak English or Spanish
  • Able to sign written informed consent and willing to follow protocol requirements
Not Eligible

You will not qualify if you...

  • Extreme mobility issues preventing study participation
  • Major thought disorders such as schizophrenia, uncontrolled bipolar disorder, or PTSD
  • History of chronic opioid use
  • Current pain level of 2 or above on a 0-10 scale
  • Uncontrolled comorbidities such as diabetes or hypertension
  • Involvement in plastic surgery for oncoplastic reconstruction
  • Received chemotherapy for current breast cancer diagnosis
  • Surgery expected to last longer than 3 hours
  • Hearing loss that could prevent hypnosedation facilitation
  • Known allergy to propofol or other medications used during surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
3
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Trial Site Locations

Total: 1 location

1

M D Anderson Cancer Center

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

L

Lorenzo Cohen, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

3

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Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery | DecenTrialz