Actively Recruiting

Age: 18Years +
FEMALE
Healthy Volunteers
NCT03923374

Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes

Led by Senthil Sadhasivam · Updated on 2025-12-18

600

Participants Needed

1

Research Sites

432 weeks

Total Duration

On this page

Sponsors

S

Senthil Sadhasivam

Lead Sponsor

E

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The objective of this study is to better understand the comprehensive integration of both clinical and genetic factors that will help to identify mothers who could be at an increased risk of poor response to opioid substitution and infants at risk of significant neonatal abstinence syndrome (NAS).

CONDITIONS

Official Title

Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age greater 18 years
  • Currently taking Buprenorphine for Opioid Use Disorder and enrolled in a prenatal opioid maintenance program in the antenatal clinic at IU Health University Hospital
  • Pregnant with single baby
  • Planned delivery at Methodist, University or Riley Hospital
Not Eligible

You will not qualify if you...

  • Serious maternal medical illness as deemed by study physician or investigator
  • Known or suspected major fetal/neonatal congenital abnormalities

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UPMC Children's Hospital

Pittsburgh, Pennsylvania, United States, 15224

Actively Recruiting

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Research Team

S

Senthil Sadhasivam, MD, MPH

CONTACT

C

Carly Riedmann, MPH

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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